Comparing single and double syringe techniques for treating tachycardia
Comparison of Double-syringe vs Single-syringe Technique of Adenosine Administration for Termination of Regular-narrow Complex Tachycardia: A Randomized, Controlled Trial
This study is testing if a simpler single-syringe method for giving adenosine can effectively treat adults with a fast heart rate called supraventricular tachycardia, compared to the traditional double-syringe method.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Khon Kaen University Academic / other |
| Locations | 1 site (Khon Kaen, Muang) |
| Trial ID | NCT05022290 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of a single-syringe technique for administering adenosine compared to the conventional double-syringe technique in patients with supraventricular tachycardia (SVT). The study aims to determine if the single-syringe method, which is less resource-intensive, is equally effective in terminating regular narrow complex tachyarrhythmias. Participants will be adults aged 18-80 who have not responded to vagal maneuvers and meet specific EKG criteria. The trial will provide randomized control data to support the efficacy of the single-syringe approach.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-80 with regular rhythm, narrow QRS complex tachyarrhythmias who have not responded to vagal maneuvers.
Not a fit: Patients experiencing acute asthmatic attacks, acute heart failure, or other serious conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could streamline the treatment process for SVT, making it more efficient and accessible in emergency settings.
How similar studies have performed: While observational studies suggest the single-syringe technique may be effective, this is the first randomized control trial to rigorously test this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18-80 years old * EKG shows regular rhythm, narrow QRS complex tachyarrhythmias (QRS complex \<0.12 msec, and rate \>150 beats per minute; bpm) * Pulse can be palpated * The tachycardia is not terminated by a vagal maneuver. Exclusion Criteria: * Acute asthmatic attack * Pregnant or tendency to be pregnant * Acute heart failure * Acute chest pain * Alteration of consciousness * Hypotension * Presenting of signs of hypoperfusion
Where this trial is running
Khon Kaen, Muang
- Department of Emergency medicine — Khon Kaen, Muang, Thailand (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.