Comparing silicone gel and estrogen cream for menopause-related symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial aims to evaluate the effectiveness of StrataMGT, a silicone gel, in managing Genitourinary Syndrome of Menopause (GSM) compared to traditional estrogen vaginal cream. Participants will be randomly assigned to receive either treatment for three months, during which their quality of life, clinical signs, symptoms, and any adverse reactions will be monitored monthly. The primary objective is to determine if StrataMGT is non-inferior to estrogen therapy in improving patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Able to provide informed consent
* Confirmed postmenopausal age
* Diagnosed genitourinary syndrome of menopause
* Access to a smartphone, tablet or computer, and to a functional email address.

Exclusion Criteria:

* Contraindication for the use of estrogen therapy
* Unable to provide informed consent
* Patient unable to apply topical device
* Allergy or intolerance to ingredients or excipients of the formulation of studied products

Where it's running

• Orange Coast Women's Medical Group
  Laguna Hills, California, United States Recruiting
• Abba Medical Group
  Miami, Florida, United States Recruiting
• One Health Research Clinic
  Johns Creek, Georgia, United States Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Telerehabilitation program for improving sexual function and reducing pain in menopausal women

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• Vaginal treatment for menopause symptoms using CO2 laser

  This study is testing if a CO2 laser treatment can help relieve vaginal dryness and discomfort in women going through menopause who can't use hormone therapy.

  Recruiting University of California, Irvine · Irvine, California · NCT06691178

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.