Comparing safety of two types of clips in gallbladder surgery

Clinical Outcomes of Absorbable or Hem-o-lok Clip Closure of the Cystic Stump in Laparoscopic Cholecystectomy: a Prospective Randomised Clinical Trial

Not applicable Interventional Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital · NCT06470360

This study is testing whether absorbable clips or Hem-o-lok clips are safer for closing the cystic duct during gallbladder surgery for patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment120 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorKartal Kosuyolu Yuksek Ihtisas Education and Research Hospital Government
Locations1 site (Istanbul, Kartal)
Trial IDNCT06470360 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the safety of absorbable clips versus Hem-o-lok clips for closing the cystic duct during laparoscopic cholecystectomy. It is a prospective randomized controlled study that will evaluate early clinical outcomes and long-term effects on surrounding anatomical structures. The study will involve patients undergoing elective laparoscopic cholecystectomy and will assess the reliability of both closure methods. By analyzing these two techniques, the trial seeks to determine which method is safer for patients.

Who should consider this trial

Good fit: Ideal candidates for this study are patients scheduled for elective laparoscopic cholecystectomy with an ASA classification of I-III.

Not a fit: Patients requiring open surgery or emergency cholecystectomy will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved safety and outcomes for patients undergoing gallbladder surgery.

How similar studies have performed: There have been no prior prospective studies comparing these two specific methods, making this approach novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* elective laparoscopic cholecystectomy ASA I-III Patients who accepted the study

Exclusion Criteria:

* open surgery emergency cholecystectomy refuse to trial

Where this trial is running

Istanbul, Kartal

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Laparoscopic Cholecystectomylaparoscopic cholecystectomycystic duct closuresafety
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.