Comparing Remimazolam and Propofol for Recovery After Upper Airway Surgery
Comparison of Remimazolam Versus Propofol-based General Anesthesia on Postoperative Quality of Recovery in Patients Undergoing Ambulatory Upper Airway Surgery: a Randomized Controlled Trial
PHASE4 · Chung-Ang University Gwangmyeong Hospital · NCT06507202
This study is testing whether remimazolam or propofol helps adults recover faster and safer after upper airway surgery.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 116 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | Chung-Ang University Gwangmyeong Hospital (other) |
| Locations | 1 site (Gyeonggi-do, Gwangmyeon-si) |
| Trial ID | NCT06507202 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effects of two anesthetic agents, remimazolam and propofol, on recovery time and safety in patients undergoing ambulatory upper airway surgeries. Participants will be randomly assigned to receive either remimazolam or propofol during their procedure, with both groups monitored for recovery indicators and adverse events in the operating room, post-anesthesia care unit, and day surgery center. The study focuses on adult patients with various upper respiratory tract conditions, assessing the efficacy of each anesthetic in facilitating a quicker and safer recovery.
Who should consider this trial
Good fit: Ideal candidates are adult patients aged 19 or older scheduled for ambulatory upper respiratory tract surgery under general anesthesia.
Not a fit: Patients who are pregnant, have a history of drug hypersensitivity, or significant liver dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery times and safety profiles for patients undergoing upper airway surgeries.
How similar studies have performed: Other studies comparing anesthetic agents have shown promising results, suggesting that this approach is both relevant and potentially beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (age 19 or older) undergoing ambulatory upper respiratory tract (nasal cavity, oral cavity, pharynx, larynx) surgery under general anesthesia * American Society of Anesthesiologists physical class classification I, II, and III Exclusion Criteria: * Patients who refused to participate in the study * Pregnant patients * Patients with a history of hypersensitivity to drugs or additives used during surgery * Patients with acute narrow-angle glaucoma * Alcohol or drug dependent patients * Patients with Child-Pugh class C liver dysfunction
Where this trial is running
Gyeonggi-do, Gwangmyeon-si
- ChungAng University Gwangmyeong Hospital — Gyeonggi-do, Gwangmyeon-si, South Korea (RECRUITING)
Study contacts
- Study coordinator: Se-Hee Min
- Email: seiheemin@gmail.com
- Phone: +820222221534
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Laryngeal Disease, Pharyngeal Diseases, Oral Cavity Disease, Nasal Disease, remimazolam, upper airway surgery, ambulatory surgery