Comparing recovery quality after two pain management techniques in knee surgery

The Quality of Recovery After Intrathecal Morphine or Adductor Canal Block Added to Spinal Anesthesia in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction

Phase 4 Interventional Cukurova University · NCT05742958

This study is testing whether using intrathecal morphine or an adductor canal block helps people recover better after knee surgery.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment70 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorCukurova University Academic / other
Locations1 site (Adana, Saricam)
Trial IDNCT05742958 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the quality of recovery in patients undergoing arthroscopic anterior cruciate ligament reconstruction using two different pain management techniques: intrathecal morphine and adductor canal block. The study utilizes the Quality of Recovery 40 (QoR-40) questionnaire to assess postoperative recovery across multiple dimensions. By comparing these two methods, the trial aims to determine which technique provides better pain control and overall recovery outcomes for patients. The research focuses on reducing opioid use and enhancing recovery speed through effective regional anesthesia techniques.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-65 with ASA physical status I or II who are scheduled for elective arthroscopic anterior cruciate ligament reconstruction.

Not a fit: Patients with coagulopathy, allergies to the studied drugs, obesity, renal or hepatic insufficiency, chronic pain syndromes, mental impairments, or those on certain medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies and faster recovery times for patients undergoing knee surgery.

How similar studies have performed: Previous studies have shown success with regional anesthesia techniques in improving postoperative recovery, making this approach both relevant and promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status I or II adult patients aged 18-65 years undergoing elective arthroscopic anterior cruciate ligament reconstruction will be included in the study.

Exclusion Criteria:

* We will exclude patients with known coagulopathy, allergies to the studied drugs, obesity (BMI \>35kg/m2), renal and/or hepatic insufficiency, chronic pain syndrome, mental impairment, depression, chronic alcoholism, and usage of antidepressant and analgesic drugs before surgery.

Where this trial is running

Adana, Saricam

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Adductor Canal BlockIntrathecal MorphineArthroscopic Anterior Cruciate Ligament ReconstructionQuality of Recoveryintrathecal morphineadductor canal blockquality of recovery
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.