Comparing recovery from two types of anesthesia for nasal bone fracture surgery

Comparative Study of Recovery Characteristics Between Remimazolam Anesthesia With Flumazenil and Desflurane Anesthesia for Closed Reduction of Nasal Bone Fracture

Not applicable Interventional Daegu Catholic University Medical Center · NCT05774366

This study is testing whether patients recovering from nasal bone fracture surgery feel better and respond faster after using one of two types of anesthesia: remimazolam or desflurane.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment58 (estimated)
Ages19 Years to 75 Years
SexAll
SponsorDaegu Catholic University Medical Center Academic / other
Locations1 site (Daegu)
Trial IDNCT05774366 on ClinicalTrials.gov

What this trial studies

This prospective, randomized study aims to evaluate the recovery characteristics of patients undergoing closed reduction of nasal bone fractures using two different anesthesia methods: remimazolam with flumazenil and desflurane. Participants will be randomly assigned to receive either remimazolam or desflurane during their procedure. The primary focus is to determine if there is a significant difference in the time it takes for patients to respond to verbal commands after the anesthetic is discontinued. This study seeks to provide insights into the effectiveness and recovery profiles of these anesthetic agents.

Who should consider this trial

Good fit: Ideal candidates are adults aged 19 to 75 with an ASA physical status of I-II undergoing elective closed reduction of nasal bone fractures.

Not a fit: Patients with cognitive impairments, chronic medication use affecting anesthesia, or significant health issues like kidney or liver disease may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved recovery times and patient outcomes in anesthesia for nasal surgeries.

How similar studies have performed: While there have been studies comparing different anesthetic agents, the specific combination of remimazolam with flumazenil in this context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 19 and 75 years
* American Society of Anesthesiologists physical status (ASA PS) of I-II
* Patients undergoing elective closed reduction of nasal bone fracture

Exclusion Criteria:

* Patient who cannot understand the process of this study
* Cognitive, visual or hearing impairment
* Chronic use of antipsychotic medications or medications for sleeping problem
* Use of benzodiazepine
* Patient with kidney or liver disease
* Body mass index (BMI) \>30 kg/m\^2

Where this trial is running

Daegu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Anesthesia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.