Comparing radiofrequency and microwave treatments for small varicose veins

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of ultrasound-guided radiofrequency ablation versus microwave ablation for treating small saphenous varicose veins. Chronic venous insufficiency is a prevalent condition, and while small saphenous varicose veins are less common, they pose unique treatment challenges. The study aims to evaluate the clinical outcomes of these two minimally invasive techniques, which may offer advantages over traditional surgical methods. Participants will be monitored for symptoms and complications following their respective treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years and ≤90 years;
* Clinical diagnosis of primary varicose veins of the lower extremities, CEAP clinical classification C2-C6, requiring treatment of the great and/or small saphenous vein segments, and at least 1 of the clinical symptoms of swelling, pain, burning sensation, heaviness, easy fatigue, itchy skin, and night cramps;
* Valve insufficiency of the great saphenous vein, small saphenous vein, or transport vein;
* Doppler ultrasound confirmation of a saphenous vein diameter greater than 3 mm and less than 12 mm in the standing position;
* Only one limb per patient was selected for inclusion in the study;
* Patients signed an informed consent form and were willing to co-operate in completing the protocol-specified investigations and follow-up visits.

Exclusion Criteria:

* Thrombosis of the great saphenous or small saphenous vein, or combined deep vein thrombosis, or previous history of deep vein thrombosis or pulmonary embolism.
* Recurrent varicose veins after previous treatment.
* Severe distortion of the great saphenous vein with anticipated catheter failure.
* Severe lower limb ischaemia (CLI) (ABPI \<0.8).
* Known allergy to medications and device materials involved in the study.
* Pre-existing implanted pacemaker, defibrillator, currently on regular anticoagulation therapy (e.g., warfarin, heparin).
* Women who are pregnant or breastfeeding.
* Unable or unwilling to complete the questionnaire.
* Participating in a study of another drug or device.
* Life expectancy \<1 year.
* Those undergoing treatment for skin malignancies other than non-melanoma.
* Daily use of narcotic drugs or non-steroidal anti-inflammatory drugs to control pain due to venous disease.
* In the judgement of the investigator, endovenous therapy is not appropriate.

Where it's running

• Hospital of Chengdu University of Traditional Chinese Medicine
  Chengdu, China Recruiting

Study contacts

• Study coordinator: Chunshui He, Doctor
• Email: Chunshuihe@msn.com
• Phone: 86-18981885601

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.