Clinical trial Recruiting at 1 site Observational Ages 18 and up

Comparing quality of life and urinary outcomes after bladder surgery

Official title: Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy

Run by Mayo Clinic · NCT06891209 · Data updated 2026-11-12

This study looks at how different types of bladder surgery affect the quality of life and urinary health of patients to see which approach might be better for them.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorMayo Clinic
Academic / other
Locations1 site (Rochester, Minnesota)
StatusRecruiting
StartedJanuary 15, 2025
Main results expectedJanuary 31, 2027
Study endsJanuary 31, 2027
Registry record updatedAugust 11, 2026
Trial IDNCT06891209 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients who have undergone partial cystectomy or are currently living with a radical cystectomy, specifically those registered in the Mayo Urology's cystectomy registry.

Probably not a fit

Patients who have had a subsequent radical cystectomy after a partial cystectomy will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the health-related quality of life (HRQOL) and urinary outcomes in patients who have undergone partial cystectomy compared to those who have had radical cystectomy. Patients will complete questionnaires to provide data on their experiences post-surgery, and their medical records will be reviewed for additional insights. The study aims to identify how various patient-specific characteristics influence these outcomes among the two groups. By comparing these cohorts, the study seeks to enhance understanding of the impacts of different surgical approaches on patient well-being.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into which surgical approach offers better quality of life and urinary function for bladder cancer patients.

How similar studies have gone: Other studies have explored similar outcomes in bladder cancer surgeries, indicating a growing interest in understanding the comparative effectiveness of surgical options.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Currently living partial cystectomy patients in Mayo Urology's cystectomy registry and patients undergoing radical or partial cystectomy
* Matched 2:1 living radical cystectomy to partial cystectomy patients
* Either urothelial or non-urothelial histology

Exclusion Criteria:

* Partial cystectomy patients that underwent subsequent radical cystectomy

Where it's running

  • Mayo Clinic in Rochester
    Rochester, Minnesota, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.