Comparing quadriceps muscle activation during straight leg raises in recovery from leg injuries

Quadriceps Activation Comparative Analysis Based on Positioning of the Ankle During Supine Straight Leg Raise and Quad Set

Observational Andrews Research & Education Foundation · NCT05568784

This study is testing how different ankle positions during straight leg raises affect muscle activation in people recovering from leg injuries, including those who have had surgery.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years to 55 Years
SexAll
SponsorAndrews Research & Education Foundation Academic / other
Locations1 site (Gulf Breeze, Florida)
Trial IDNCT05568784 on ClinicalTrials.gov

What this trial studies

This observational study aims to compare quadriceps muscle activation in patients recovering from lower extremity injuries, particularly focusing on the effects of ankle positioning during straight leg raise exercises. Participants will include both healthy individuals and those who have undergone surgery, such as ACL reconstruction. The study seeks to understand how different ankle positions influence muscle activation, which is crucial for rehabilitation and preventing muscle atrophy. By examining these factors, the research hopes to enhance recovery protocols for individuals with quadriceps atrophy.

Who should consider this trial

Good fit: Ideal candidates for this study are males and females aged 18-55 who are recovering from lower extremity injuries or surgeries.

Not a fit: Patients with a history of cancer, neurological disorders, or recent musculoskeletal injuries to the quadriceps may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation strategies that minimize quadriceps atrophy and enhance recovery outcomes for patients with leg injuries.

How similar studies have performed: While this study builds on existing knowledge of quadriceps rehabilitation, it specifically investigates the impact of ankle positioning, which may provide novel insights into recovery strategies.

Eligibility criteria

Show full inclusion / exclusion criteria
(All Participants)

Inclusion Criteria:

* Males and females ages 18-55

Exclusion Criteria:

* History of diagnosed cancer, neurological disorder, peripheral nerve injury affecting the lower limb or injury to the lower spine with radicular symptoms, which may affect quadriceps activation
* History of musculoskeletal injury to the quadriceps that may affect ability to maintain muscle contractions without excessive fatigue or discomfort

(Healthy Participants)

Exclusion Criteria:

* Injury to the knee or quadriceps muscle group within the past 12 months to the tested side
* History of lower extremity orthopedic surgery in the past 12 months to the tested side

Where this trial is running

Gulf Breeze, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Quadriceps Muscle AtrophyLeg Injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.