Comparing pulsed radiofrequency therapy and adductor canal blockade for knee osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the efficacy and safety of ultrasound-guided pulsed radiofrequency therapy compared to adductor canal blockade in patients suffering from knee osteoarthritis. The study focuses on individuals who have had knee osteoarthritis for more than six months and are not suitable candidates for surgical intervention. Participants will be randomly assigned to receive either treatment, and their pain levels will be assessed using the Knee Injury and Osteoarthritis Outcome Score (KOOS) before and after the interventions. The study has received ethical approval and aims to provide insights into non-surgical pain relief options for knee osteoarthritis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnose of the Knee osteoarthritis confirmed by orthopedic examination
* K-L grades 3 and 4
* A sufficient level of education to understand study procedures
* Be able to communicate with site personnel
* Age \>45 years

Exclusion Criteria :

* Any cardiovascular, hepatic, or renal conditions that would compromise participation, in the opinion of the investigator
* Severe neurologic conditions interfere with a knee condition
* Narcotic dependent (opioid intake of more than 3 months and more than 30 mg of daily oral morphine equivalents)
* Coexisting severe hematological disorder or deranged coagulation parameters
* Psychiatric illnesses
* Allergy to any of the drugs used in the study
* Infection or malignancy at the site of the block
* Any active systemic infection
* Implanted electronic devices like spinal cord stimulators, cardiac pacemakers or similar

Where it's running

• University Medical Centre
  Ljubljana, Slovenia Recruiting

Study contacts

• Principal investigator: Mensur Salihovic — University Medical Centre Ljubljana
• Study coordinator: Mensur Salihovic, MD
• Email: mensur.salihovic@kclj.si
• Phone: +38640208892

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.