Comparing pulsed radiofrequency therapy and adductor canal blockade for knee osteoarthritis
Comparison of the Effectiveness of Pulsed Radiofrequency Therapy and Canal Adductor Blockade for Chronic Pain and Functioning in Knee Osteoarthritis
This study is testing whether pulsed radiofrequency therapy or adductor canal blockade can help people with knee osteoarthritis feel less pain without needing surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 128 (estimated) |
| Ages | 45 Years to 100 Years |
| Sex | All |
| Sponsor | University Medical Centre Ljubljana Academic / other |
| Locations | 1 site (Ljubljana) |
| Trial ID | NCT05962463 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the efficacy and safety of ultrasound-guided pulsed radiofrequency therapy compared to adductor canal blockade in patients suffering from knee osteoarthritis. The study focuses on individuals who have had knee osteoarthritis for more than six months and are not suitable candidates for surgical intervention. Participants will be randomly assigned to receive either treatment, and their pain levels will be assessed using the Knee Injury and Osteoarthritis Outcome Score (KOOS) before and after the interventions. The study has received ethical approval and aims to provide insights into non-surgical pain relief options for knee osteoarthritis.
Who should consider this trial
Good fit: Ideal candidates are individuals over 45 years old with a confirmed diagnosis of knee osteoarthritis at K-L grades 3 and 4.
Not a fit: Patients with severe cardiovascular, hepatic, or renal conditions, or those with significant neurological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide effective non-surgical pain relief options for patients with knee osteoarthritis.
How similar studies have performed: Other studies have shown promising results with similar interventions, indicating potential efficacy in pain management for knee osteoarthritis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnose of the Knee osteoarthritis confirmed by orthopedic examination * K-L grades 3 and 4 * A sufficient level of education to understand study procedures * Be able to communicate with site personnel * Age \>45 years Exclusion Criteria : * Any cardiovascular, hepatic, or renal conditions that would compromise participation, in the opinion of the investigator * Severe neurologic conditions interfere with a knee condition * Narcotic dependent (opioid intake of more than 3 months and more than 30 mg of daily oral morphine equivalents) * Coexisting severe hematological disorder or deranged coagulation parameters * Psychiatric illnesses * Allergy to any of the drugs used in the study * Infection or malignancy at the site of the block * Any active systemic infection * Implanted electronic devices like spinal cord stimulators, cardiac pacemakers or similar
Where this trial is running
Ljubljana
- University Medical Centre — Ljubljana, Slovenia (Recruiting)
Study contacts
- Principal investigator: Mensur Salihovic — University Medical Centre Ljubljana
- Study coordinator: Mensur Salihovic, MD
- Email: mensur.salihovic@kclj.si
- Phone: +38640208892
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.