Comparing pulpotomy and root canal treatment for irreversible pulpitis
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis: A Randomised Control Trial
This study is testing whether a new tooth treatment called pulpotomy works better than the traditional root canal for people with painful irreversible pulpitis in their back teeth.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 380 (estimated) |
| Ages | 12 Years and up |
| Sex | All |
| Sponsor | British University In Egypt Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05726357 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the long-term outcomes of full pulpotomy compared to traditional root canal treatment in patients with symptomatic irreversible pulpitis. It focuses on patients with mature permanent molars or premolars that are restorable and can be isolated during treatment. The study will assess the effectiveness of vital pulp therapy in alleviating symptoms and preserving tooth vitality. High-quality evidence is sought to enhance current knowledge regarding treatment options for this dental condition.
Who should consider this trial
Good fit: Ideal candidates for this study are adults with symptomatic irreversible pulpitis in mature permanent molars or premolars that are restorable.
Not a fit: Patients with active periodontal disease, complex medical histories, or those who are pregnant or breastfeeding may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a less invasive treatment option for patients suffering from irreversible pulpitis, potentially preserving more natural tooth structure.
How similar studies have performed: While there is ongoing research in vital pulp therapy, this specific comparison of pulpotomy versus root canal treatment in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * a mature permanent tooth * symptoms indicative of IRP * responsive to cold and EPT sensibility testing * restorable and can be adequately isolated during treatment * One tooth (molar or premolar) per patient. Exclusion Criteria: * active periodontal disease * complex medical histories * unable to consent * pregnant or breast-feeding * excessive bleeding that cannot be controlled
Where this trial is running
Cairo
- Faculty of Dentistry — Cairo, Egypt (Recruiting)
Study contacts
- Principal investigator: shehabeldin Saber — Professor of Endodontics
- Study coordinator: Shehabeldin Saber, phD
- Email: shehabeldin.saber@bue.edu.eg
- Phone: +202 26890000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.