Comparing Propofol and Dexmedetomidine for Preventing Agitation in Children After Surgery
Efficacy of Propofol Versus Dexmedetomidine to Prevent Emergence Agitation After Sevoflurane Anesthesia in Children Undergoing Squint Surgery
This study is testing whether Propofol or Dexmedetomidine works better to help young children stay calm and comfortable after squint surgery.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 3 Years to 7 Years |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06312618 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of Propofol and Dexmedetomidine in preventing emergence agitation in pediatric patients aged 3 to 7 years undergoing squint surgery with sevoflurane anesthesia. The study will assess which of the two medications is more effective in reducing symptoms such as restlessness and disorientation following surgery. By focusing on children, the trial addresses a common issue in pediatric anesthesia, aiming to improve recovery experiences. The study is interventional and is classified as Phase 4.
Who should consider this trial
Good fit: Ideal candidates for this study are pediatric patients aged 3 to 7 years classified as ASA Physical Status Class I or II who are scheduled for squint surgery.
Not a fit: Patients younger than 3 years or older than 7 years, those with ASA classification III or higher, or those with a history of allergies to the study medications will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery experiences for children undergoing surgery by effectively preventing emergence agitation.
How similar studies have performed: Other studies have shown varying degrees of success in using similar approaches to manage emergence agitation in pediatric patients, but this specific comparison is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients from 3 to 7 years. * American Society of Anesthesiologists (ASA) Physical Status Class-I and II. * Patients undergo squint surgery. Exclusion Criteria: * Declining to give written informed consent by patient legal guardian. * Age younger than 3 years or older than 7 years. * ASA classification ≥ III. * History of allergy to the medications used in the study or egg products. * Psychiatric disorder * Other co-morbidities or congenital anomalies or neurological.
Where this trial is running
Cairo
- Ain Shams University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Nada Helal, MSc
- Email: nada.mousa@med.asu.edu.eg
- Phone: 1091513200
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.