Comparing pressure pad versus pressure bandage immobilisation for snakebite first aid in healthy adults
Efficacy of Pressure Pad vs Pressure Bandage Immobilisation for Snake Bite First Aid in Healthy Volunteers.
This test will see if a pressure pad works as well as the standard pressure bandage at slowing the spread of a mock venom in healthy adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Townsville University Hospital Academic / other |
| Locations | 1 site (Hyde Park, Queensland) |
| Trial ID | NCT07261982 on ClinicalTrials.gov |
What this trial studies
This interventional study enrolls healthy adult volunteers to compare two first-aid methods—pressure bandage immobilisation and a simpler pressure pad—plus a no-first-aid control. A radiolabelled mock venom (Technetium-99m sulphur colloid) is used and its movement through lymphatic and soft-tissue pathways is tracked with imaging while the assigned first-aid method is applied. The primary comparison is how effectively each technique limits distal movement of the tracer, indicating potential to slow venom spread. Results will inform whether the simpler pressure pad provides comparable containment to the current recommended bandage technique.
Who should consider this trial
Good fit: Adults aged 18 or older who are healthy with no lymphatic, cardiac, peripheral vascular, renal, hepatic, or lymphatic malignancy conditions, not pregnant or breastfeeding, and not allergic to Technetium-99m sulphur colloid are eligible.
Not a fit: People who are under 18, pregnant or breastfeeding, have the listed exclusionary medical conditions, or are allergic to the tracer, as well as patients already envenomed and needing antivenom, are unlikely to gain direct benefit from participating.
Why it matters
Potential benefit: If successful, this could identify a simpler, easier-to-teach first aid method that slows venom spread as well as the current pressure bandage, improving pre-hospital care for snakebites.
How similar studies have performed: The pressure bandage immobilisation method is long-established but has limited experimental human data, and the pressure pad approach is relatively novel with little prior clinical testing.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years old or greater * No known or clinically evident lymphatic condition (eg. lymphoedema, lymph node surgery etc) * No known cardiac failure * No known peripheral vascular disease * No known renal or hepatic impairment * No known lymphoma Exclusion Criteria: * Age less than 18 years old * Pregnant * Breast feeding * Allergy to Technetium-99m sulphur colloid * Presence of any of the conditions mentioned in the inclusion criteria
Where this trial is running
Hyde Park, Queensland
- Queensland X-Ray — Hyde Park, Queensland, Australia (Recruiting)
Study contacts
- Principal investigator: Adam L Holyoak — Townsville University Hospital
- Study coordinator: Adam L Holyoak
- Email: adam.holyoak@health.qld.gov.au
- Phone: +61423852272
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.