Comparing Prednisolone and Cerebrolysin for treating Bell's Palsy
Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy
This study is testing whether Prednisolone or Cerebrolysin works better to help people with Bell's Palsy recover and avoid complications.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | October 6 University Academic / other |
| Locations | 1 site (Giza) |
| Trial ID | NCT05821075 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of two treatments, Prednisolone and Cerebrolysin, for patients suffering from Bell's Palsy, a condition characterized by sudden facial paralysis. The study aims to determine which of the two interventions provides better outcomes in terms of recovery and reduction of complications associated with the condition. Participants will be monitored for improvements in facial function and any adverse effects related to the treatments. The trial is designed to gather data from patients with acute unilateral facial palsy without identifiable causes.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals experiencing unilateral acute facial palsy with no identifiable cause.
Not a fit: Patients with recurrent Bell's Palsy, certain medical conditions like diabetes or severe hypertension, or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for patients with Bell's Palsy, potentially improving recovery times and reducing complications.
How similar studies have performed: While corticosteroids are commonly used for Bell's Palsy, the use of Cerebrolysin is less established, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * unilateral acute facial palsy of no identifiable cause Exclusion Criteria: * Recurrent facial Bell's palsy * Pregnancy * Diabetes * Epilepsy * Severe hypertension, * Renal or hepatic disease, * Gastric or duodenal ulcer * presence of acute otitis media or ipsilateral chronic otitis * Recent head injury, * psychiatric disease * If there is any contraindications for corticosteroids
Where this trial is running
Giza
- October 6 university hospital — Giza, Egypt (Recruiting)
Study contacts
- Study coordinator: Engy Wahsh
- Email: engywahsh@o6u.edu.eg
- Phone: 01003095692
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.