Comparing platelet-rich fibrin and plasma for treating female pattern hair loss

A Randomized, Split-head Comparison Study of the Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients : A Pilot Study

NA · Siriraj Hospital · NCT06440655

This study is testing whether platelet-rich fibrin or platelet-rich plasma is better and safer for treating women with female pattern hair loss.

Quick facts

PhaseNA
Study typeInterventional
Enrollment10 (estimated)
Ages20 Years to 55 Years
SexFemale
SponsorSiriraj Hospital (other)
Locations2 sites (Bangkok Noi, Bangkok and 1 other locations)
Trial IDNCT06440655 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the efficacy and safety of two treatments, platelet-rich fibrin and platelet-rich plasma, in women experiencing female pattern hair loss. Participants will receive three treatments of either intervention at one-month intervals, followed by follow-up assessments at four and six months post-treatment. The study will help determine which treatment is more effective and safer for this condition.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 20-55 diagnosed with female pattern hair loss classified as Ludwig Type 2.

Not a fit: Patients who are pregnant, lactating, or have certain medical conditions such as platelet dysfunction or active smoking may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective treatment option for women suffering from hair loss.

How similar studies have performed: Previous studies have shown promising results with platelet-rich plasma in hair restoration, but the comparison with platelet-rich fibrin is less explored.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 20-55 years
* Female
* Subject who was diagnosed with Female pattern hair loss in Ludwig Classification 2 (part width 2-4 centimeters) by Dermatologist

Exclusion Criteria:

* Pregnancy or Lactation subjects
* Subject with history of platelet dysfunction, low platelet, anemia, cirrhosis, cancer, or immunocompromised host
* Subject who are active smoking and alcoholism
* Subject who has dermatitis, scar or infection at intervention area
* Subject who has history of allergy to anesthesia drug
* Subject who taking NSAIDs, Hormonal drug, anticoagulants drug
* Subject who has psychiatric condition diagnosed by psychiatrist
* Subject who are not allowed to take a photo

Where this trial is running

Bangkok Noi, Bangkok and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Female Pattern Hair Loss, Platelet-Rich Plasma, Platelet-rich Fibrin, female pattern hair loss, platelet-rich plasma, platelet-rich fibrin

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.