Comparing photobiostimulation and pulsed electromagnetic field treatments for chronic rhinosinusitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of photobiostimulation and pulsed electromagnetic field therapy on adults suffering from chronic rhinosinusitis. It aims to evaluate improvements in quality of life, pulmonary function, headache frequency, total nasal symptoms, and mean platelet volume. Participants will undergo these non-invasive treatments to assess their effectiveness compared to traditional therapies. The study targets individuals aged 20 to 40 with mild to moderate symptoms and confirmed allergies to common perennial allergens.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Participants suffering from mild to moderate symptoms (baseline Total nasal symptoms score ≤ 9).
2. Subjects age range from 20 to 40 years old.
3. Patients of both sexes.
4. proven positive allergy test (skin prick test or multiple allergen simultaneous test) to any of the common perennial allergens such as dust mites, molds, insects, and animal dander within the last 12 months

Exclusion Criteria:

* Pregnant or breastfeeding women.
* Patients with a definite deviated nasal septum, or history of operation within the last 6 months.
* Hypertension, diabetes mellitus, malignancy, active pulmonary tuberculosis, active respiratory disease like asthma, or other systemic diseases.
* Long-term use of corticosteroids or immunosuppressive agents.
* Participation in another clinical study within 30 days.
* Hyperthyroidism
* Patients who had used antihistamines within 1 week, topical corticosteroids within 2 weeks, systemic corticosteroids within 4 weeks, anticholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, nonsteroidal analgesics within 2 weeks, and other drugs that the researchers believed were inappropriate.
* Patients with Tattoos, moles and dark skin

Where it's running

• out-patient clinic, faculty of physical therapy, October University for Modern Sciences and Arts
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Samar Said Abd AL-razek, physical therapist
• Email: samar.said.alfiqy@gmail.com
• Phone: +201156644369

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Low-level laser therapy plus home exercise for moderate knee osteoarthritis and nearby muscle loss

  This trial tests whether adding low-level laser therapy to a home exercise program helps people over 50 with moderate (Kellgren-Lawrence grade 2–3) knee osteoarthritis improve pain, cartilage thickness, and nearby muscle loss.

  Recruiting Ankara Etlik City Hospital · Ankara, YENIMAHALLE · NCT07078877

• Bacteriophage therapy for hard-to-treat infections

  This study is testing if a new treatment using bacteriophages can help people with tough infections that don’t respond to regular medicines.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT06368388

• Impact of CFTR Modulators on Sinus Health in Young Children with Cystic Fibrosis

  This study is testing if a new treatment for cystic fibrosis can improve sinus health and smell in young children aged 2-8.

  Recruiting at 6 sites University of California, Los Angeles · Aurora, Colorado and 5 other locations · NCT06191640

• Applying Betamethasone Cream to Sinuses After Surgery for Chronic Rhinosinusitis

  This study is testing if applying a special cream to the sinuses after surgery can help people with chronic sinus issues feel better when other treatments haven't worked.

  Recruiting at 4 sites Phase 2 Oticara Australia PTY LTD · Sydney, New South Wales and 3 other locations · NCT05882903

• Using probiotics in nasal irrigation to treat chronic sinusitis

  This study is testing if using a probiotic nasal rinse can help people with chronic sinusitis feel better after they've had sinus surgery, compared to using a regular saline rinse.

  Recruiting Phase 2 University of Illinois Chicago · Chicago, Illinois · NCT05427695

• Exploring the nasal microbiome's role in diseases like chronic rhinosinusitis and COVID-19

  This study looks at the bacteria in the nose of healthy people and those with smell problems from COVID-19 or chronic sinus issues to see how it might affect their health and treatment options.

  Recruiting University of Aarhus · Holstebro, Central Jutland · NCT05061329

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.