Comparing photobiostimulation and pulsed electromagnetic field treatments for chronic rhinosinusitis

Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis

Not applicable Interventional Cairo University · NCT06986629

This study tests whether two new treatments, light therapy and electromagnetic field therapy, can help adults with chronic sinus issues feel better compared to standard treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages20 Years to 40 Years
SexAll
SponsorCairo University Academic / other
Locations1 site (Cairo)
Trial IDNCT06986629 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of photobiostimulation and pulsed electromagnetic field therapy on adults suffering from chronic rhinosinusitis. It aims to evaluate improvements in quality of life, pulmonary function, headache frequency, total nasal symptoms, and mean platelet volume. Participants will undergo these non-invasive treatments to assess their effectiveness compared to traditional therapies. The study targets individuals aged 20 to 40 with mild to moderate symptoms and confirmed allergies to common perennial allergens.

Who should consider this trial

Good fit: Ideal candidates are adults aged 20 to 40 with mild to moderate chronic rhinosinusitis symptoms and a positive allergy test.

Not a fit: Patients with severe systemic diseases, recent surgeries, or those on long-term corticosteroids may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a non-invasive treatment option that significantly improves the quality of life for patients with chronic rhinosinusitis.

How similar studies have performed: Other studies have shown promise with similar non-invasive therapies, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Participants suffering from mild to moderate symptoms (baseline Total nasal symptoms score ≤ 9).
2. Subjects age range from 20 to 40 years old.
3. Patients of both sexes.
4. proven positive allergy test (skin prick test or multiple allergen simultaneous test) to any of the common perennial allergens such as dust mites, molds, insects, and animal dander within the last 12 months

Exclusion Criteria:

* Pregnant or breastfeeding women.
* Patients with a definite deviated nasal septum, or history of operation within the last 6 months.
* Hypertension, diabetes mellitus, malignancy, active pulmonary tuberculosis, active respiratory disease like asthma, or other systemic diseases.
* Long-term use of corticosteroids or immunosuppressive agents.
* Participation in another clinical study within 30 days.
* Hyperthyroidism
* Patients who had used antihistamines within 1 week, topical corticosteroids within 2 weeks, systemic corticosteroids within 4 weeks, anticholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, nonsteroidal analgesics within 2 weeks, and other drugs that the researchers believed were inappropriate.
* Patients with Tattoos, moles and dark skin

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PhotobiostimulationPulsed Electromagnetic FiledLow Level Laser TherapyChronic RhinosinusitisQuality of Life
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.