Comparing partial and total knee replacement for knee disease
Partial Versus Total Knee Replacement in Bicompartmental Gonarthrosis (Medial and Patellofemoral): Prospective Functional Assessment Study
This study is testing whether partial knee replacement or total knee replacement helps people with knee disease recover better and feel more satisfied after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 48 (estimated) |
| Ages | 40 Years to 85 Years |
| Sex | All |
| Sponsor | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Academic / other |
| Locations | 1 site (Milan) |
| Trial ID | NCT06305858 on ClinicalTrials.gov |
What this trial studies
This study evaluates the recovery outcomes of patients undergoing partial knee replacement versus total knee replacement for bicompartmental gonarthrosis. It involves a randomized approach with 48 adult patients divided into two groups: one receiving partial knee replacement and the other total knee replacement with patellar resurfacing. The primary outcome is measured using the KSS questionnaire at one month post-surgery, alongside other functional assessments at multiple follow-up points. The goal is to determine which surgical approach yields better functional recovery and patient satisfaction.
Who should consider this trial
Good fit: Ideal candidates are adults aged 40 to 85 with grade 3-4 medial gonarthrosis and intact ligaments.
Not a fit: Patients with cognitive impairments, psychiatric disorders, or those outside the age range of 40 to 85 may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical options and recovery outcomes for patients with bicompartmental knee disease.
How similar studies have performed: Previous studies have shown promising results with partial knee replacements, suggesting potential benefits over total knee replacements, but this specific comparison is less commonly explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Grade 3-4 sec Kellgren-Lawrence medial gonarthrosis * Patellar symptoms * Primary gonarthrosis * Patients with ligament integrity * Age between 40 and 85 years inclusive * Signing of the Informed Consent and consent to cooperate in all study procedures. Exclusion Criteria: * Cognitive impairment * Psychiatric disorders * Neuromuscular disorders * Age \> 85 years and \<40 years * Lateral gonarthrosis grade 4 sec Kellgren-Lawrence * Secondary medial gonarthrosis * Revisions * Minors * Pregnant women self-declaration
Where this trial is running
Milan
- Istituto Clinico San Siro — Milan, Italy (Recruiting)
Study contacts
- Study coordinator: Elena Cittera
- Email: elena.cittera@grupposandonato.it
- Phone: 0283502224
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.