Comparing pain relief methods for lumbar spine surgery

Echo-guided Transverse Abdominal Plane Block (TAP) in Anterior Lumbar Arthrodesis (ALIF): Randomized, Double-blind, Controlled Trial.

Not applicable Interventional Clinique Saint Jean, France · NCT06002217

This study is testing if a special pain relief method using a TAP block can help people who have had lumbar spine surgery need less pain medication afterward.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years and up
SexAll
SponsorClinique Saint Jean, France Academic / other
Locations1 site (Montpellier)
Trial IDNCT06002217 on ClinicalTrials.gov

What this trial studies

This interventional study aims to evaluate the effectiveness of a transverse abdominal plane (TAP) block using levobupivacaine compared to a placebo in patients undergoing anterior lumbar spine surgery. Participants will be randomly assigned to receive either the TAP block or a placebo, and their postoperative pain medication usage will be monitored over a three-day period. The primary goal is to determine if the TAP block can significantly reduce the need for pain medication after surgery.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years old scheduled for abdominal disc surgery with ASA criteria 1, 2, or 3.

Not a fit: Patients with allergies to local anesthetics or those undergoing cancer or trauma surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved pain management and reduced reliance on opioids after lumbar spine surgery.

How similar studies have performed: Previous studies have shown promising results with TAP blocks in various surgical settings, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patient affiliated or entitled to a social security plan.

* Patient who has been informed about the study and has co-signed a consent form with the investigator. consent to participate in the study.
* Patients over 18 years of age scheduled for abdominal disc surgery on one or two levels.
* Patient with ASA criteria 1, 2 and 3.

Exclusion Criteria:

* Patients with intolerance or contraindication to paracetamol, anti-inflammatory or morphine.
* Patients allergic to local anesthetics.
* Pregnant or breast-feeding patient.
* patient undergoing cancer or trauma surgery trauma.
* Patient participating in another interventional study.
* Patient with a history of lumbar arthrodesis.
* Patient refusing to sign consent form.
* Patient unable to give informed consent.
* Patient under court protection, guardianship or trusteeship.
* Patient not available for study follow-up.

Where this trial is running

Montpellier

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Fusion of Spine, Lumbar Region
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.