Comparing pain relief methods for gynecologic surgery
The Comparison of Effectiveness Between Epidural Combined Bilateral US TAP Block Versus Epidural Alone for Gynaecology Operation.
NA · Universiti Sains Malaysia · NCT06425484
This study is testing whether adding a specific pain relief technique to an epidural can help women feel less pain after gynecologic surgery compared to just using the epidural alone.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 46 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Universiti Sains Malaysia (other) |
| Locations | 1 site (Kubang Kerian, Kelantan) |
| Trial ID | NCT06425484 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of an epidural combined with a bilateral ultrasound-guided transversus abdominis plane (TAP) block versus an epidural alone in patients undergoing elective major laparotomy for gynecologic procedures. Participants will be randomized into two groups: one receiving the combined treatment and the other receiving only the epidural. Pain scores and the requirement for epidural infusion will be assessed postoperatively by a blinded acute pain service team. The study will involve approximately 46 subjects and will last about two days for each participant.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and above scheduled for elective major laparotomy gynecologic procedures.
Not a fit: Patients with contraindications for epidural or TAP block procedures, or those with chronic pain or psychological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing gynecologic surgeries.
How similar studies have performed: Previous studies have shown promising results with similar approaches in pain management, suggesting potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Elective major laparotomy gynaecology procedure. * Age 18 years and above * ASA I, II, III Exclusion Criteria: * Prolonged INR * Allergic to LA * History of chronic pain * Psychological disorder/addict to opioid or benzodiazepine * Any contraindication for epidural or TAP block procedure * Pregnancy
Where this trial is running
Kubang Kerian, Kelantan
- Universiti Sains Malaysia — Kubang Kerian, Kelantan, Malaysia (RECRUITING)
Study contacts
- Principal investigator: Munirah Abdul Majid — University Sains Malaysia
- Study coordinator: Rhendra Hardy Mohd Zain
- Email: rhendra@gmail.com
- Phone: +6097676104
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gynecologic Disease