Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

Comparing pain relief methods for breast cancer surgery

Official title: Comparative Study Between Ultrasound Guided Mid-point Transverse Process to Pleura Block And Erector Spinae Plane Block For Perioperative Analgesia In Modified Radical Mastectomy In Breast Cancer Patients

Run by National Cancer Institute, Egypt · NCT06888258 · Data updated 2026-11-12

This study is testing two different pain relief methods to see which one helps people feel better after breast cancer surgery.

Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment90 (estimated)
SponsorNational Cancer Institute, Egypt
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedOctober 1, 2024
Main results expectedNovember 1, 2025
Study endsFebruary 1, 2026
Registry record updatedMarch 26, 2025
Trial IDNCT06888258 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients classified as ASA I-II who are scheduled for modified radical mastectomy and have a BMI between 18.5 and 30 kg/m2.

Probably not a fit

Patients with known allergies to local anesthetics, bleeding disorders, or those classified as ASA III-IV may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of two different analgesic techniques, the Erector Spinae Plane block and the mid-point transverse process to pleura block, in patients undergoing modified radical mastectomy for breast cancer. Participants will be randomly assigned to one of the two groups, where they will receive ultrasound-guided injections of bupivacaine to assess pain relief post-surgery. The study will monitor the efficacy of these blocks in managing postoperative pain, which is crucial for recovery and patient comfort.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast cancer surgery.

How similar studies have gone: Previous studies have shown promising results with similar analgesic techniques, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA I-II.
* Undergoing modified radical mastectomy surgery.
* Body mass index (BMI) from 18.5 to 30 kg/m2

Exclusion Criteria:

* Patient refusal.
* Known allergy to local anesthetics.
* Bleeding disorders; platelets count \<50,000 , prothrombin concentration \< 60% or any coagulopathy disorder.
* Use of any anti-coagulants.
* Inability to provide informed consent.
* ASA III-IV.
* Neurological disorders.
* Patient with psychiatric disorders

Where it's running

  • National cancer institute, Cairo University
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.