Comparing pain relief methods for breast cancer surgery
Official title: Comparative Study Between Ultrasound Guided Mid-point Transverse Process to Pleura Block And Erector Spinae Plane Block For Perioperative Analgesia In Modified Radical Mastectomy In Breast Cancer Patients
Run by National Cancer Institute, Egypt · NCT06888258 · Data updated 2026-11-12
This study is testing two different pain relief methods to see which one helps people feel better after breast cancer surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | National Cancer Institute, Egypt Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | October 1, 2024 |
| Main results expected | November 1, 2025 |
| Study ends | February 1, 2026 |
| Registry record updated | March 26, 2025 |
| Trial ID | NCT06888258 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients classified as ASA I-II who are scheduled for modified radical mastectomy and have a BMI between 18.5 and 30 kg/m2.
✕Probably not a fit
Patients with known allergies to local anesthetics, bleeding disorders, or those classified as ASA III-IV may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of two different analgesic techniques, the Erector Spinae Plane block and the mid-point transverse process to pleura block, in patients undergoing modified radical mastectomy for breast cancer. Participants will be randomly assigned to one of the two groups, where they will receive ultrasound-guided injections of bupivacaine to assess pain relief post-surgery. The study will monitor the efficacy of these blocks in managing postoperative pain, which is crucial for recovery and patient comfort.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast cancer surgery.
How similar studies have gone: Previous studies have shown promising results with similar analgesic techniques, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA I-II. * Undergoing modified radical mastectomy surgery. * Body mass index (BMI) from 18.5 to 30 kg/m2 Exclusion Criteria: * Patient refusal. * Known allergy to local anesthetics. * Bleeding disorders; platelets count \<50,000 , prothrombin concentration \< 60% or any coagulopathy disorder. * Use of any anti-coagulants. * Inability to provide informed consent. * ASA III-IV. * Neurological disorders. * Patient with psychiatric disorders
Where it's running
-
National cancer institute, Cairo University
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: mahmoud Saad Mahmoud Mohamed Mohamed, Msc
- Email: doc.mahmoudsaad@gmail.com
- Phone: +201094555375
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.