Comparing pain relief methods for breast cancer surgery
Comparative Study Between Ultrasound Guided Mid-point Transverse Process to Pleura Block And Erector Spinae Plane Block For Perioperative Analgesia In Modified Radical Mastectomy In Breast Cancer Patients
This study is testing two different pain relief methods to see which one helps people feel better after breast cancer surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | National Cancer Institute, Egypt Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06888258 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of two different analgesic techniques, the Erector Spinae Plane block and the mid-point transverse process to pleura block, in patients undergoing modified radical mastectomy for breast cancer. Participants will be randomly assigned to one of the two groups, where they will receive ultrasound-guided injections of bupivacaine to assess pain relief post-surgery. The study will monitor the efficacy of these blocks in managing postoperative pain, which is crucial for recovery and patient comfort.
Who should consider this trial
Good fit: Ideal candidates include patients classified as ASA I-II who are scheduled for modified radical mastectomy and have a BMI between 18.5 and 30 kg/m2.
Not a fit: Patients with known allergies to local anesthetics, bleeding disorders, or those classified as ASA III-IV may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast cancer surgery.
How similar studies have performed: Previous studies have shown promising results with similar analgesic techniques, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA I-II. * Undergoing modified radical mastectomy surgery. * Body mass index (BMI) from 18.5 to 30 kg/m2 Exclusion Criteria: * Patient refusal. * Known allergy to local anesthetics. * Bleeding disorders; platelets count \<50,000 , prothrombin concentration \< 60% or any coagulopathy disorder. * Use of any anti-coagulants. * Inability to provide informed consent. * ASA III-IV. * Neurological disorders. * Patient with psychiatric disorders
Where this trial is running
Cairo
- National cancer institute, Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: mahmoud Saad Mahmoud Mohamed Mohamed, Msc
- Email: doc.mahmoudsaad@gmail.com
- Phone: +201094555375
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.