Comparing pain relief methods after wisdom tooth surgery
A COMPARISON OF ANALGESIC EFFICACY OF TRANSDERMAL DICLOFENAC AND ORAL COMBINATION OF PARACETAMOL AND IBUPROFEN IN POSTOPERATIVE PAIN MANAGEMENT FOLLOWING SURGICAL EXTRACTION OF MANDIBULAR THIRD MOLAR
This study is testing whether a skin patch with pain medicine works better than taking pills for managing pain after getting wisdom teeth removed.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 108 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | B.P. Koirala Institute of Health Sciences Academic / other |
| Locations | 1 site (Dharān Bāzār, Koshi) |
| Trial ID | NCT06146491 on ClinicalTrials.gov |
What this trial studies
This interventional study compares the effectiveness of a transdermal diclofenac patch with an oral combination of paracetamol and ibuprofen for managing postoperative pain following the surgical extraction of mandibular third molars. Patients will be randomly assigned to one of the two treatment groups, and their pain levels will be monitored through telephonic interviews at specified intervals post-surgery. The study aims to determine which method provides better pain relief while ensuring patient safety and comfort.
Who should consider this trial
Good fit: Ideal candidates for this study are patients classified as ASA I and ASA II who are scheduled for surgical extraction of mandibular third molars.
Not a fit: Patients with hypersensitivity to the study medications, those on anticoagulant or corticosteroid therapy, or those with certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing wisdom tooth extraction.
How similar studies have performed: Other studies have shown varying degrees of success with similar pain management approaches, but this specific comparison is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:Patients of ASA I and ASA II, who are consenting for the study. Patient indicated for surgical extraction of mandibular third molar - Exclusion Criteria:Hypersensitivity to local anesthetic agent Patient who are physically and mentally healthy Patient not consenting to participate in the study Pregnant females in their first and third trimester of pregnancy. Patients allergic to diclofenac and oral combination of Paracetamol and Ibuprofen. Patient taking any analgesic at the time of surgery. Patient on anticoagulant therapy. Patient under Corticosteroids therapy. Patient needing pre-operative antibiotics prophylaxis Patient having peptic ulcerative disease. Patient having acute localized infection like pericoronitis. -
Where this trial is running
Dharān Bāzār, Koshi
- Niroj khanal — Dharān Bāzār, Koshi, Nepal (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.