Comparing pain relief methods after total abdominal hysterectomy

Ultrasound Guided Versus Surgical Rectus Sheath Block Versus Local Anesthesia Infiltration for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy: A Randomized Trial

Not applicable Interventional Ain Shams University · NCT06837532

This study is testing three different ways to manage pain after a total abdominal hysterectomy to see which one works best for patients aged 18 to 65.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment90 (estimated)
Ages18 Years to 65 Years
SexFemale
SponsorAin Shams University Academic / other
Locations1 site (Cairo)
Trial IDNCT06837532 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness and safety of three different methods for postoperative pain management in patients undergoing total abdominal hysterectomy: ultrasound-guided rectus sheath block, surgical rectus sheath block, and local anesthesia infiltration. The research will involve patients aged 18 to 65 who are scheduled for elective surgery and will assess pain relief outcomes and any associated complications. By comparing these techniques, the study seeks to identify the most effective approach for managing postoperative pain in this surgical population.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 to 65 scheduled for elective total abdominal hysterectomy with ASA physical status I or II.

Not a fit: Patients with hepatic, renal, or cardiac diseases, known allergies to local anesthetics, or those with chronic analgesic use may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing total abdominal hysterectomy.

How similar studies have performed: Previous studies have shown varying success with similar analgesic techniques, but this specific comparison is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age from 18 to 65 years old.
* American Society of Anesthesiologists (ASA) physical status I - II.
* Patients scheduled for elective total abdominal hysterectomy under general anesthesia.

Exclusion Criteria:

* Hepatic, renal or cardiac disease.
* Any known allergy to local anesthetic.
* Physical or mental conditions which may vaguely measure postoperative pain following surgery.
* History of chronic use of analgesic as nonsteroidal anti-inflammatory drugs (NSAIDs) or central nervous system (CNS) depressants as antiepileptic, and bleeding disorders.

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions UltrasoundSurgicalRectus Sheath BlockLocal Anesthesia InfiltrationPostoperative AnalgesiaTotal Abdominal Hysterectomy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.