Comparing pain relief methods after knee replacement surgery
Comparison of Three Different Analgesic Nerve Blocks in Total Knee Replacement Surgery
This study is testing which of three different pain relief methods works best for people after knee replacement surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 180 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Azienda Ospedaliero, Universitaria Pisana Academic / other |
| Locations | 1 site (Pisa, Tuscany) |
| Trial ID | NCT06422585 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the effectiveness of three different regional anesthesia techniques for pain management in patients undergoing total knee replacement surgery. Participants will receive selective spinal anesthesia followed by one of the three nerve blocks: Femoral Nerve Group+IPACK, Saphenous Nerve block+IPACK, or Subsartorial Block. The study will evaluate the pain control experienced by patients in the 24 hours post-surgery to determine if any technique provides superior analgesia. The research will involve monitoring patients and administering standard pain relief medications as needed.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old scheduled for elective total knee replacement surgery.
Not a fit: Patients under 18, those requiring general anesthesia, or individuals with certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing knee replacement surgery.
How similar studies have performed: Previous studies have shown varying success with different regional anesthesia techniques, but this specific comparison is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 y/o * Total knee replacement elective surgery * Informed consent Exclusion Criteria: * Age \< 18 y/o * Surgery with general anesthesia * Patients with coagulopaties * Patients in chronic opioid therapy * Refuse to sign informed consent form * Unable to sign informed consent form * Know allergies to medication used for analgesia
Where this trial is running
Pisa, Tuscany
- Edificio 3 - Azienda Ospedaliero Universitaria Pisana Cisanello — Pisa, Tuscany, Italy (Recruiting)
Study contacts
- Study coordinator: Serena Ricalzone, MD
- Email: serenaricalzone@gmail.com
- Phone: 050.997881
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.