Comparing pain relief methods after hip surgery

Peri-incisional Local Infiltration to Improve Pain Control After Periacetabular Osteotomy

Phase2; Phase3 Interventional University of Iowa · NCT06519955

This study is testing different ways to use local anesthesia during hip surgery to see which method helps young patients feel less pain afterward.

Quick facts

PhasePhase2; Phase3
Study typeInterventional
Enrollment120 (estimated)
Ages13 Years to 50 Years
SexAll
SponsorUniversity of Iowa Academic / other
Locations1 site (Iowa City, Iowa)
Trial IDNCT06519955 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of different peri-incisional local infiltrative anesthesia (PLIA) techniques in reducing post-operative pain for patients aged 13 to 50 undergoing periacetabular osteotomy (PAO) due to hip dysplasia. Participants will be randomly assigned to one of three groups: no PLIA, PLIA administered after incision closure, or PLIA throughout the surgery. The study will assess post-operative pain levels and medication usage through surveys and medical record reviews. The goal is to determine the impact of PLIA on pain management and recovery outcomes.

Who should consider this trial

Good fit: Ideal candidates are adolescents and young adults diagnosed with hip dysplasia who are scheduled for PAO at the University of Iowa Hospital and Clinics.

Not a fit: Patients who are pregnant, breastfeeding, or have allergies to the study medications will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing hip surgery.

How similar studies have performed: Previous studies have shown promising results with similar approaches to pain management, suggesting potential for success in this trial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adolescent or young adult diagnosed with hip dysplasia indicated for PAO at University of Iowa Hospital and Clinics.

Exclusion Criteria:

* Unable to provide informed consent.
* Pregnant or breast-feeding individuals
* Prisoner or ward of the state
* Allergy or medical contradiction to any of the study medications
* Patients undergoing femoral osteotomy or surgical hip dislocation with PAO will be excluded

Where this trial is running

Iowa City, Iowa

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hip DysplasiaPeriacetabular OsteotomyPLIAPeri-Incisional Local Infiltrative Anesthesia
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.