Comparing pain relief from dexketoprofen and ibuprofen in long bone fractures
Comparison of Analgesic Efficacy of Dexketoprofen and Ibuprofen in Long Bone Fractures: Randomised Controlled Double-blind Study
This study is testing whether dexketoprofen or ibuprofen works better to relieve pain for people with long bone fractures.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Ankara City Hospital Bilkent Academic / other |
| Locations | 1 site (Ankara) |
| Trial ID | NCT06060236 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effectiveness of two common analgesics, ibuprofen and dexketoprofen, in managing pain for patients with long bone fractures, such as those of the tibia, femur, and humerus. Long bone fractures typically result from trauma and are associated with significant pain and mobility limitations. By evaluating the pain relief and side effects of each medication, the study seeks to determine which drug provides better outcomes for patients. The research is particularly relevant as there is limited literature on this specific comparison in clinical practice.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 80 who have a long bone fracture and a pain score of 50 or above.
Not a fit: Patients under 18 or over 80, those with other significant injuries, or those with a history of adverse reactions to NSAIDs may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients with long bone fractures.
How similar studies have performed: While there is limited research specifically comparing these two drugs for long bone fractures, studies on NSAIDs for pain management have shown varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * over 18 years * Patients under 80 years of age * Patients who agreed to participate in the study * One of the tibia, femur and humerus bones is broken * Patients with a VAS score of 50 and above * Patients with no other injuries requiring emergency surgery * Previously known adverse reactions to the active ingredient of the drugs to be used patients with no history * Conscious patients * Oriented cooperative patients Exclusion Criteria: * Patients under the age of 18 and over the age of 80 * Patients who did not agree to participate in the study * Patients with vital signs outside the normal limits * Patients with a history of adverse reactions to known NSAIDs * Those who cannot determine the severity of pain on the VAS * Patients with a VAS Score of 50 mm or less * Those with other orthopedic injuries pregnant women * Those with advanced systemic disease * Those with malignancy * Those with chronic liver and kidney disease * Those who use neuro-psychiatric drugs with sedative and analgesic effects * Those with a history of psychological and neurological diseases * Patients using analgesics 8 hours before the examination
Where this trial is running
Ankara
- Ankara Bilkent Şehir Hastanesi — Ankara, Turkey (Recruiting)
Study contacts
- Principal investigator: Safa Dönmez, MD — Ankara City Hospital Bilkent
- Study coordinator: Safa Dönmez, MD
- Email: drsafa0131@gmail.com
- Phone: +905537515545
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.