Comparing pain relief effects of upper and lower limb resistance training
Official title: Exercise-Induced Hypoalgesia Differences at Proximal and Distal Regions After Applying a Lower Limb Resistance Training or an Upper Limb Resistance Training Protocol: A Randomized Controlled Trial in Healthy Participants
Run by Centro Universitario La Salle · NCT06765486 · Data updated 2026-11-12
This study tests whether doing resistance exercises for the upper or lower body can help healthy people feel less pain after working out.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 64 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Centro Universitario La Salle Academic / other |
| Locations | 1 site (Madrid) |
| Status | Recruiting |
| Started | February 15, 2025 |
| Main results expected | May 20, 2025 |
| Study ends | June 1, 2025 |
| Registry record updated | February 26, 2025 |
| Trial ID | NCT06765486 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy individuals aged 18 to 64 without any history of pain or significant medical conditions.
✕Probably not a fit
Patients with cardiovascular, respiratory, metabolic, neurological, or osteomuscular conditions, or those experiencing pain, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial investigates the effects of resistance training on exercise-induced hypoalgesia in healthy individuals. Participants will be divided into three groups: one performing lower limb resistance exercises, another focusing on upper limb exercises, and a control group. The study will measure pressure pain thresholds in both the thigh and elbow to assess differences in pain relief between the trained regions. The goal is to determine how different resistance training interventions influence local and distal hypoalgesia.
Why it matters
Potential benefit: If successful, this study could provide insights into optimizing resistance training for pain management.
How similar studies have gone: While there is existing research on exercise-induced hypoalgesia, this specific comparison of upper and lower limb resistance training is a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Asymptomatic subjects aged between 18 and 64 years. Exclusion Criteria: * Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies. * History of epilepsy. * Pregnant. * Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 12 weeks.
Where it's running
-
CSEU LaSalle
Madrid, Spain Recruiting
Study contacts
- Study coordinator: Álvaro Reina-Varona, MSc
- Email: alvaro.reina@lasallecampus.es
- Phone: (+34) 91 740 19 80
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.