Comparing pain management techniques in hip and knee replacement surgeries
Postoperative Analgesia in Patients Undergoing Hip and Knee Replacement Surgery - a Study Comparing Ultrasound-guided Nerve Blocks With Intraoperative Local Anesthetic Infiltration or Opioids
This study is testing if adding regional pain blocks to standard pain management can help people recovering from hip or knee replacement surgeries feel less pain and use fewer opioids.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Region Skane Academic / other |
| Locations | 1 site (Trelleborg) |
| Trial ID | NCT06230081 on ClinicalTrials.gov |
What this trial studies
This study evaluates the impact of adding regional blocks with local anesthetics on postoperative pain, opioid consumption, and functional outcomes in patients undergoing total hip or knee arthroplasty due to osteoarthritis. A total of 400 patients will be randomized into two groups: one receiving standard pain management and the other receiving additional regional blocks. The study will assess the effectiveness of these interventions in improving recovery and reducing reliance on opioids. The anesthesia protocols will be tailored based on patient preferences and clinical guidelines.
Who should consider this trial
Good fit: Ideal candidates are patients with osteoarthritis of the knee or hip who require total knee or hip replacement.
Not a fit: Patients with known allergies to local anesthetics, coagulopathy, or those undergoing bilateral or revision arthroplasties may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and reduced opioid use for patients undergoing joint replacement surgeries.
How similar studies have performed: Other studies have shown promising results with regional anesthesia techniques in similar surgical contexts, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Osteoarthritis of the knee- or hip necessitating total knee- or hip replacement * Patients who understand the conditions of the study and are willing to participate for the length of the prescribed follow-up Exclusion Criteria: * Known allergy to local anesthetics or other contraindication for the use of local anesthetics. * Coagulopathy * Bilateral operation * Revision arthroplasty
Where this trial is running
Trelleborg
- Dept of Anaesthesiology, Trelleborg Hospital — Trelleborg, Sweden (Recruiting)
Study contacts
- Principal investigator: Gunnar Flivik, MD PhD — Department of Orthopedics, Skane Univ Hosp
- Study coordinator: Gunnar Flivik, MD PhD
- Email: gunnar.flivik@med.lu.se
- Phone: +46 46 173538
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.