Comparing pain levels after using buffered and non-buffered articaine for dental treatment
A Comparison of Pain Response During Administration of Buffered Articaine Versus Non-buffered Articaine Local Anesthetics for Dental Treatment in Adult
This study tests if using a special version of articaine that’s buffered can help reduce pain during dental treatments compared to the regular version.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 108 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Cleveland Dental Institute Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Trial ID | NCT06538233 on ClinicalTrials.gov |
What this trial studies
This study investigates the differences in pain experienced by patients receiving buffered versus non-buffered articaine during dental procedures. It involves administering two types of articaine to participants who require dental treatment in the upper anterior region. The study aims to determine if buffering the anesthetic reduces pain compared to the standard non-buffered version. Participants will be monitored for pain levels following the administration of the anesthetic.
Who should consider this trial
Good fit: Ideal candidates are healthy males and females aged 18 to 60 who need dental treatment in the upper anterior region.
Not a fit: Patients with periodontally affected teeth, radiographic bone loss, or abnormal tooth length may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management techniques in dental procedures.
How similar studies have performed: Other studies have shown varying results regarding the effectiveness of buffered anesthetics, making this approach both relevant and potentially novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Males and females, age- 18 to 60 yrs. * Medically free. * Need a dental treatment in the upper anterior region. Exclusion Criteria: * Periodontally affected teeth. * Radiographic bone loss. * Upnormal length of the teeth.
Where this trial is running
Cleveland, Ohio
- Clevland Dental Institute — Cleveland, Ohio, United States (Recruiting)
Study contacts
- Principal investigator: Waleed Elmallah, PhD — Cleveland Dental Institute
- Study coordinator: Pavanpreet Kaur, Resident
- Email: p.kaur@cdiohio.org
- Phone: 2163551155
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.