Comparing pain control methods after kidney transplant
Wound Catheter Vs LA Bolus in Renal Transplant: RCT
This study is testing whether a continuous pain relief method after kidney transplant works better than a single pain injection to help patients feel more comfortable and recover faster.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 88 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | The Leeds Teaching Hospitals NHS Trust Academic / other |
| Locations | 2 sites (Leeds and 1 other locations) |
| Trial ID | NCT06011421 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of Continuous Local Anaesthetic Infiltration via Wound Catheter (LAWC) compared to a one-time Local Anaesthetic (LA) injection for pain management following kidney transplantation. Patients will be randomly assigned to receive either the standard LA injection or the LAWC method, which delivers local anaesthetic continuously over time. The study aims to assess outcomes such as the amount of morphine needed for pain control, overall pain quality, and recovery improvements. By comparing these two approaches, the study seeks to identify the most effective pain management strategy for kidney transplant patients.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals undergoing primary single kidney transplantation who can provide informed consent.
Not a fit: Patients who have undergone midline laparotomy, dual kidney transplantation, kidney re-transplantation, multi-organ transplantation, are on long-term opiates, or have psychiatric illnesses may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to better pain management and improved recovery for kidney transplant patients.
How similar studies have performed: Similar studies using continuous local anaesthetic techniques in other surgical specialties have shown promising results, suggesting potential success for this approach in kidney transplantation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Primary kidney transplantation * Single kidney transplantation * Signed informed Consent Exclusion Criteria: * Midline laparotomy * Dual kidney transplantation * Kidney re-transplantation * Multi-organ transplantation * Patients on Long term opiates * Patients with psychiatric illness
Where this trial is running
Leeds and 1 other locations
- Leeds Teaching Hospital NHS Trust — Leeds, United Kingdom (Recruiting)
- Leeds Teaching Hospitals NHS Trust — Leeds, United Kingdom (Completed)
Study contacts
- Study coordinator: Sonsoles Martinez-Lopez
- Email: sonsoles.martinez-lopez@nhs.net
- Phone: 0113 243 3144
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.