Comparing pain after root canal treatment using two different sealers
Evalution of Postoperative Pain With Resin Based Sealer vs Zinc Oxide Eugenol Sealer After Single Visit Endodontic
This study tests whether using a resin-based or a zinc oxide eugenol-based sealer during a root canal affects pain levels in patients after the treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Pakistan Institute of Medical Sciences Government |
| Locations | 1 site (Islamabad) |
| Trial ID | NCT06013293 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate postoperative pain levels in patients undergoing single visit endodontic treatment using either a resin-based sealer or a zinc oxide eugenol-based sealer. A total of 100 patients with symptomatic irreversible pulpitis will be randomly assigned to one of the two treatment groups. Pain levels will be assessed using a visual analog scale before and after the procedure. The study will ensure informed consent and adherence to strict inclusion and exclusion criteria to maintain patient safety and data integrity.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 65 with symptomatic irreversible pulpitis requiring root canal treatment.
Not a fit: Patients with ASA classification 3 to 5, immature apices, or those with severe periodontal issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify the most effective sealer for minimizing postoperative pain in endodontic treatments.
How similar studies have performed: Previous studies have shown varying results regarding the effectiveness of different sealers in endodontics, making this approach both relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patient who agree to participate in study 2. ASA CLASSIFICATION 1or 2 3. Minimum age of 18years old and maximum age of 65 years old 4. Maxillary and Mandibular single rooted teeth included in the study 5. Patient with symptomatic irreversible pulpitis with either normal apical tissue or symptomatic apical periodontitis. Exclusion Criteria: - 1. ASA Classification 3 to 5 2. Patient with immature apices and root resorption will be excluded from the study. 3. Severe periodontal problem. 4. Vertical or horizontal root fractures will be excluded from the study 5. Patients who will be already on analgesia within 24 hours excluded from study 6. Those requiring root canal treatment of two or more teeth ipsilaterally (since the pain caused by any of these teeth can result in false positive reading) will be excluded
Where this trial is running
Islamabad
- School of Dentistry — Islamabad, Pakistan (Recruiting)
Study contacts
- Study coordinator: Ahsen Amin, BDS
- Email: ahsen_amin@hotmail.com
- Phone: 03315161642
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.