Comparing Oxytocin and Carbetocin during Cesarean Sections
Official title: Van Yuzuncu Yil University Faculty of Medicine Ethics Committee
Run by Yuzuncu Yil University · NCT06956365 · Data updated 2026-11-12
This study is testing whether oxytocin or carbetocin is better at managing blood flow and reducing blood loss during cesarean sections for women aged 18-40.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 80 (estimated) |
| Sponsor | Yuzuncu Yil University Academic / other |
| Locations | 1 site (Van, Tuşba) |
| Status | Recruiting |
| Started | May 14, 2024 |
| Main results expected | May 30, 2025 |
| Study ends | July 30, 2025 |
| Registry record updated | May 4, 2025 |
| Trial ID | NCT06956365 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are pregnant women aged 18-40 years scheduled for elective cesarean sections with an ASA score of I-II.
✕Probably not a fit
Patients who prefer spinal or epidural anesthesia or those with significant comorbidities such as hypertension or diabetes may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to compare the effects of two uterotonics, oxytocin and carbetocin, on hemodynamic changes during elective cesarean section surgeries. It will involve 80 patients aged 18-40 years, who will be randomly assigned to receive either oxytocin or carbetocin after general anesthesia induction. Hemodynamic parameters and intraoperative blood loss will be meticulously recorded at various intervals during the surgery to assess the efficacy of each drug. The study is designed as a double-blind trial to ensure unbiased results.
Why it matters
Potential benefit: If successful, this study could lead to improved management of intraoperative hemodynamics during cesarean sections, potentially reducing complications.
How similar studies have gone: Previous studies have shown varying results with uterotonics in cesarean sections, making this approach both relevant and necessary for further exploration.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for caesarean sections * Between 18-40 years * ASA I-II group * Those who will undergo general anesthesia * Those between 35-40 weeks of pregnancy * 1st and 2nd caesarean sections Exclusion Criteria: * Those who prefer spinal or epidural anesthesia * Those who are outside the age range of 18-40 * Those who are ASA III and above * Those with HT, DM, cardiac and respiratory diseases * Preeclampsia, eclampsia, HELLP * Those with a history of drug use that affects the cardiovascular system * Placenta Previa, Placenta Acreta, Placenta Acreta
Where it's running
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Van Yuzuncu Yil University
Van, Tuşba, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Nurettin NK Kurt, assoc.Prof.
- Email: dr.nurettinkurt@gmail.com
- Phone: +90 4322150473
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Effects of massage and exercises on cesarean scar and recovery
This study tests whether direct scar massage or indirect massage plus exercise helps people recover after a cesarean birth and reduces scar-related pain.
-
Reflexology and hand massage after cesarean section
This study tests whether reflexology hand massage or stroking hand massage can reduce anxiety and increase satisfaction, and how they affect heart/blood pressure after cesarean delivery.
-
Health education to see if primigravida women choose vaginal delivery more often
A health education program is being tested to see if it helps first-time pregnant women in choosing vaginal delivery over unnecessary cesareans.
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Enhanced Recovery Adherence and Recovery Quality After Cesarean Delivery
This study tests whether following enhanced recovery after cesarean delivery protocols is linked with better recovery quality in women having a planned cesarean with spinal anesthesia.
-
Predictors of severe pain within 24 hours after cesarean delivery with spinal anesthesia
This study will look at which pre-, intra-, and post-operative factors are linked to severe pain in the first 24 hours after an elective cesarean done with spinal anesthesia.
-
Steri-Strips added to standard wound closure after cesarean delivery
This study tests whether adding Steri-Strips after a C-section helps reduce wound problems for pregnant patients.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.