Comparing Oxytocin and Carbetocin during Cesarean Sections
Van Yuzuncu Yil University Faculty of Medicine Ethics Committee
This study is testing whether oxytocin or carbetocin is better at managing blood flow and reducing blood loss during cesarean sections for women aged 18-40.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | Yuzuncu Yil University Academic / other |
| Locations | 1 site (Van, Tuşba) |
| Trial ID | NCT06956365 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effects of two uterotonics, oxytocin and carbetocin, on hemodynamic changes during elective cesarean section surgeries. It will involve 80 patients aged 18-40 years, who will be randomly assigned to receive either oxytocin or carbetocin after general anesthesia induction. Hemodynamic parameters and intraoperative blood loss will be meticulously recorded at various intervals during the surgery to assess the efficacy of each drug. The study is designed as a double-blind trial to ensure unbiased results.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women aged 18-40 years scheduled for elective cesarean sections with an ASA score of I-II.
Not a fit: Patients who prefer spinal or epidural anesthesia or those with significant comorbidities such as hypertension or diabetes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of intraoperative hemodynamics during cesarean sections, potentially reducing complications.
How similar studies have performed: Previous studies have shown varying results with uterotonics in cesarean sections, making this approach both relevant and necessary for further exploration.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for caesarean sections * Between 18-40 years * ASA I-II group * Those who will undergo general anesthesia * Those between 35-40 weeks of pregnancy * 1st and 2nd caesarean sections Exclusion Criteria: * Those who prefer spinal or epidural anesthesia * Those who are outside the age range of 18-40 * Those who are ASA III and above * Those with HT, DM, cardiac and respiratory diseases * Preeclampsia, eclampsia, HELLP * Those with a history of drug use that affects the cardiovascular system * Placenta Previa, Placenta Acreta, Placenta Acreta
Where this trial is running
Van, Tuşba
- Van Yuzuncu Yil University — Van, Tuşba, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Nurettin NK Kurt, assoc.Prof.
- Email: dr.nurettinkurt@gmail.com
- Phone: +90 4322150473
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.