Comparing oxycodone and sufentanil for pain management after laparoscopic hysterectomy
Official title: The Efficacy and Safety of Oxycodone in Patient-controlled Intravenous Analgesia After Laparoscopic Hysterectomy
Run by Affiliated Hospital of Nantong University · NCT06690307 · Data updated 2026-11-12
This study is testing whether oxycodone or sufentanil works better for managing pain after laparoscopic hysterectomy surgery.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 65 Years |
| Sex | Women only |
| Enrollment | 64 (estimated) |
| Sponsor | Affiliated Hospital of Nantong University Academic / other |
| Locations | 1 site (Nantong, Jiangsu) |
| Status | Recruiting |
| Started | December 3, 2024 |
| Main results expected | December 31, 2025 |
| Study ends | July 31, 2026 |
| Registry record updated | December 4, 2024 |
| Trial ID | NCT06690307 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 65 who are scheduled for selective laparoscopic hysterectomy and classified as ASA I-III.
✕Probably not a fit
Patients with allergies to the study drugs, preoperative opioid use, or significant organ dysfunction may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness and safety of oxycodone versus sufentanil in patient-controlled intravenous analgesia (PCIA) for patients undergoing laparoscopic hysterectomy. Participants will be divided into two groups, with one receiving oxycodone and the other receiving sufentanil for pain management. Pain levels will be assessed at various intervals post-surgery, and the use of additional pain relief medications and any adverse effects will be monitored. The goal is to identify the most effective analgesic approach for postoperative pain management in this surgical context.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients recovering from laparoscopic hysterectomy.
How similar studies have gone: Previous studies have shown varying success with different analgesics in postoperative settings, but this specific comparison of oxycodone and sufentanil in PCIA is less commonly explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * selective laparoscopic hysterectomy * general anesthesia * ASA classification I - III * aged 18 - 65 years Exclusion Criteria: * allergy to oxycodone or any other drugs will be used in the study * preoperative opioids medication * opioids abuse * hepatic or renal dysfunction * cardiovascular or pulmonary dysfunction * lack of full civil capacity or refuse to participate
Where it's running
-
Affiliated hospital of Nantong University
Nantong, Jiangsu, China Recruiting
Study contacts
- Study coordinator: Siyuan Liu, PhD
- Email: tdfylsy@ntu.edu.cn
- Phone: +86-85050301
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.