Comparing oxycodone and sufentanil for pain management after laparoscopic hysterectomy
The Efficacy and Safety of Oxycodone in Patient-controlled Intravenous Analgesia After Laparoscopic Hysterectomy
This study is testing whether oxycodone or sufentanil works better for managing pain after laparoscopic hysterectomy surgery.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 64 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | Female |
| Sponsor | Affiliated Hospital of Nantong University Academic / other |
| Locations | 1 site (Nantong, Jiangsu) |
| Trial ID | NCT06690307 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness and safety of oxycodone versus sufentanil in patient-controlled intravenous analgesia (PCIA) for patients undergoing laparoscopic hysterectomy. Participants will be divided into two groups, with one receiving oxycodone and the other receiving sufentanil for pain management. Pain levels will be assessed at various intervals post-surgery, and the use of additional pain relief medications and any adverse effects will be monitored. The goal is to identify the most effective analgesic approach for postoperative pain management in this surgical context.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 65 who are scheduled for selective laparoscopic hysterectomy and classified as ASA I-III.
Not a fit: Patients with allergies to the study drugs, preoperative opioid use, or significant organ dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients recovering from laparoscopic hysterectomy.
How similar studies have performed: Previous studies have shown varying success with different analgesics in postoperative settings, but this specific comparison of oxycodone and sufentanil in PCIA is less commonly explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * selective laparoscopic hysterectomy * general anesthesia * ASA classification I - III * aged 18 - 65 years Exclusion Criteria: * allergy to oxycodone or any other drugs will be used in the study * preoperative opioids medication * opioids abuse * hepatic or renal dysfunction * cardiovascular or pulmonary dysfunction * lack of full civil capacity or refuse to participate
Where this trial is running
Nantong, Jiangsu
- Affiliated hospital of Nantong University — Nantong, Jiangsu, China (Recruiting)
Study contacts
- Study coordinator: Siyuan Liu, PhD
- Email: tdfylsy@ntu.edu.cn
- Phone: +86-85050301
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.