Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 18 to 65 Women only

Comparing oxycodone and sufentanil for pain management after laparoscopic hysterectomy

Official title: The Efficacy and Safety of Oxycodone in Patient-controlled Intravenous Analgesia After Laparoscopic Hysterectomy

Run by Affiliated Hospital of Nantong University · NCT06690307 · Data updated 2026-11-12

This study is testing whether oxycodone or sufentanil works better for managing pain after laparoscopic hysterectomy surgery.

Quick facts

PhasePhase 4
Study typeInterventional
Ages18 Years to 65 Years
SexWomen only
Enrollment64 (estimated)
SponsorAffiliated Hospital of Nantong University
Academic / other
Locations1 site (Nantong, Jiangsu)
StatusRecruiting
StartedDecember 3, 2024
Main results expectedDecember 31, 2025
Study endsJuly 31, 2026
Registry record updatedDecember 4, 2024
Trial IDNCT06690307 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 65 who are scheduled for selective laparoscopic hysterectomy and classified as ASA I-III.

Probably not a fit

Patients with allergies to the study drugs, preoperative opioid use, or significant organ dysfunction may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness and safety of oxycodone versus sufentanil in patient-controlled intravenous analgesia (PCIA) for patients undergoing laparoscopic hysterectomy. Participants will be divided into two groups, with one receiving oxycodone and the other receiving sufentanil for pain management. Pain levels will be assessed at various intervals post-surgery, and the use of additional pain relief medications and any adverse effects will be monitored. The goal is to identify the most effective analgesic approach for postoperative pain management in this surgical context.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients recovering from laparoscopic hysterectomy.

How similar studies have gone: Previous studies have shown varying success with different analgesics in postoperative settings, but this specific comparison of oxycodone and sufentanil in PCIA is less commonly explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* selective laparoscopic hysterectomy
* general anesthesia
* ASA classification I - III
* aged 18 - 65 years

Exclusion Criteria:

* allergy to oxycodone or any other drugs will be used in the study
* preoperative opioids medication
* opioids abuse
* hepatic or renal dysfunction
* cardiovascular or pulmonary dysfunction
* lack of full civil capacity or refuse to participate

Where it's running

  • Affiliated hospital of Nantong University
    Nantong, Jiangsu, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.