Comparing outcomes of salvage and radical cystectomy for bladder cancer
Salvage Cystectomy vs Radical Cystectomy, a Comparative Study
This study is testing whether patients with bladder cancer do better after a standard surgery or a follow-up surgery if their initial treatment didn't work, looking at their recovery and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 40 Years and up |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Assiut, أسيوط) |
| Trial ID | NCT06115434 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the operative difficulties, types of urinary diversion, intraoperative and postoperative complications, and quality of life in patients who have undergone radical cystectomy versus those who have had salvage cystectomy after bladder preservation therapy. Radical cystectomy is the standard treatment for muscle-invasive bladder cancer, but some patients may opt for bladder-sparing therapy, which can lead to the need for salvage cystectomy if the initial treatment fails. The study will evaluate the differences in surgical outcomes and patient quality of life between these two approaches.
Who should consider this trial
Good fit: Ideal candidates include patients with muscle-invasive bladder cancer who are either undergoing salvage cystectomy or have opted for bladder preservation protocols.
Not a fit: Patients with metastatic bladder cancer or those who refuse to participate in the study may not receive any benefit.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the best surgical approaches for bladder cancer patients, potentially improving their quality of life and surgical outcomes.
How similar studies have performed: Other studies have explored the outcomes of radical versus salvage cystectomy, but this specific comparison in the context of bladder preservation therapy is less commonly addressed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with muscle invasive bladder cancer ≥ cT2N0/xM0 who underwent salvage cystectomy / going for bladder preservation protocol. * patients with muscle invasive bladder cancer underwent radical cystectomy. Exclusion Criteria: * Patients refusing to participate in our study. * patients with metastatic bladder cancer
Where this trial is running
Assiut, أسيوط
- Assiut university hospital — Assiut, أسيوط, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohamed AbdulMawgoud, MBBCH
- Email: mohamedsalah003@gmail.com
- Phone: 1011486957
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.