Comparing outcomes of minimally invasive and open esophagectomy for esophageal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study assesses the short and long-term outcomes of patients undergoing minimally invasive esophagectomy (MIE) compared to those undergoing open esophagectomy for esophageal cancer. It focuses on both standard clinical outcomes, such as morbidity and mortality, and patient-derived outcomes, particularly quality of life (QOL) as measured by the MOS SF36 questionnaire. The study aims to evaluate the effectiveness of the SF36 in reflecting changes in clinical status and to compare these results with disease-specific scales related to dysphagia and reflux. Additionally, it examines the impact of adjuvant or neoadjuvant therapy on QOL in this patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients scheduled for MIE (Minimally Invasive Esophagectomy)
* Patients scheduled for open esophagectomy
* Signed informed consent

Exclusion Criteria:

* Patients who are unable to comprehend or complete the QOL instruments.
* Patients less than 18 years of age.

Where it's running

• University of Pittsburgh Medical Center - Department of Cardiothoracic Surgery
  Pittsburgh, Pennsylvania, United States Recruiting
• UPMC - Hillman Cancer Center
  Pittsburgh, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: James D Luketich, MD — UPMC - Department of Cardiothoracic Surgery
• Study coordinator: Julie A Ward, BSN
• Email: wardj@upmc.edu
• Phone: 412-647-8583

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.