Comparing osteoporosis risk factors in people after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will recruit adults aged 55–85 with a prior ischemic or hemorrhagic stroke treated at Ankara Etlik City Hospital. Participants between one week and six months or more than one year after stroke will receive bone mineral density (BMD) scans and clinical data collection. Researchers will compare BMD results and clinical risk factors to determine which features are associated with osteoporosis development after stroke. Patients with prior osteoporosis treatment, prior fragility fractures, secondary causes of osteoporosis, other major neurological or psychiatric diseases, or hip prostheses are excluded to limit confounding.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Diagnosis of ischemic or hemorrhagic stroke
2. Between 1 week and 6 months or \>1 year has passed since the date of the event
3. Being between 55 and 85 years of age

Exclusion Criteria:

1. The patient has additional neurological conditions besides stroke
2. The patient has a psychiatric condition
3. History of recurrent stroke
4. BMD scan performed within the last year for stroke patients
5. Having received osteoporosis treatment before or after the stroke
6. The patient having a fragility fracture before the stroke
7. The patient having a hip fracture or hip prosthesis
8. The patient having an additional condition that affects physical function before the stroke (amputation, severe fracture)
9. The patient has an additional disease or medication use that could cause secondary osteoporosis
10. The patient's stroke did not cause physical function loss Inclusion Criteria for Non-Stroke Controls

No history of ischemic or hemorrhagic stroke.

Being between 55 and 85 years of age.

Ability to undergo the required clinical assessments and DXA measurements.

Exclusion Criteria for Non-Stroke Controls

Presence of a neurological condition causing significant physical functional impairment.

Presence of a psychiatric condition that may interfere with participation in the study or completion of assessments.

History of any cerebrovascular event, including transient ischemic attack.

Having undergone a BMD scan within the last year.

Having received osteoporosis treatment.

History of fragility fracture.

History of hip fracture or presence of a hip prosthesis.

Presence of any medical or musculoskeletal condition causing significant physical functional impairment or mobility limitations (e.g., amputation or severe fracture).

Presence of any disease or medication use associated with secondary osteoporosis.

Where it's running

• Ankara Etlik City Hospital
  Ankara, Yenimahalle, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Ayşe Naz Kalem, Specialist — Ankara Etlik City Hospital
• Study coordinator: Ayşe Naz Kalem Özgen, specialist
• Email: kalemnaz@gmail.com
• Phone: +90 312 797 00 00

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.