Comparing osteoporosis risk factors in people after stroke
Comparison of Osteoporosis Risk in the Subacute and Chronic Periods Following Stroke and Evaluation of Factors Increasing Osteoporosis
This project will see if stroke itself and related health factors lead to lower bone density in people aged 55–85 who had an ischemic or hemorrhagic stroke.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 84 (estimated) |
| Ages | 55 Years to 85 Years |
| Sex | All |
| Sponsor | Ankara Etlik City Hospital Government |
| Locations | 1 site (Ankara, Yenimahalle) |
| Trial ID | NCT07228611 on ClinicalTrials.gov |
What this trial studies
This observational study will recruit adults aged 55–85 with a prior ischemic or hemorrhagic stroke treated at Ankara Etlik City Hospital. Participants between one week and six months or more than one year after stroke will receive bone mineral density (BMD) scans and clinical data collection. Researchers will compare BMD results and clinical risk factors to determine which features are associated with osteoporosis development after stroke. Patients with prior osteoporosis treatment, prior fragility fractures, secondary causes of osteoporosis, other major neurological or psychiatric diseases, or hip prostheses are excluded to limit confounding.
Who should consider this trial
Good fit: Ideal candidates are adults 55–85 who had a single ischemic or hemorrhagic stroke 1 week–6 months or more than 1 year ago, who have not received osteoporosis treatment and have no other neurological, psychiatric, or bone conditions that affect mobility or bone health.
Not a fit: People who had prior osteoporosis treatment, previous fragility or hip fractures, hip prostheses, recurrent strokes, secondary causes of osteoporosis, or other major pre-stroke mobility-limiting conditions are excluded and would not gain direct benefit from this study.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify stroke survivors at high risk for bone loss so they can receive earlier bone density testing or preventive treatment.
How similar studies have performed: Previous observational research has shown that bone loss and fracture risk increase after stroke, but direct comparisons of multiple post-stroke risk factors remain limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Followed by ischemic or hemorrhagic stroke 2. Between 1 week and 6 months or \>1 year has passed since the date of the event 3. Being between 55 and 85 years of age Exclusion Criteria: 1. The patient has additional neurological conditions besides stroke 2. The patient has a psychiatric condition 3. History of recurrent stroke 4. BMD scan performed within the last year for stroke patients 5. Having received osteoporosis treatment before or after the stroke 6. The patient having a fragility fracture before the stroke 7. The patient having a hip fracture or hip prosthesis 8. The patient having an additional condition that affects physical function before the stroke (amputation, severe fracture) 9. The patient has an additional disease or medication use that could cause secondary osteoporosis 10. The patient's stroke did not cause physical function loss
Where this trial is running
Ankara, Yenimahalle
- Ankara Etlik City Hospital — Ankara, Yenimahalle, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Ayşe Naz Kalem Özgen, specialist
- Email: kalemnaz@gmail.com
- Phone: +90 0312 797 00 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.