Comparing Ortho MTA cement and AH Plus bioceramic sealer for root canal treatment
Clinical Outcome of Root Canal Treatment With Ortho MTA (BioMTA®) Cement and AH Plus® Bioceramic Sealer (Dentsply). A Randomized Controlled Trial.
NA · National University Hospital, Singapore · NCT05984940
This study is testing whether a new root canal material called Ortho MTA works better than the standard gutta-percha and AH Plus sealer for healing infected teeth in adults.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 21 Years to 95 Years |
| Sex | All |
| Sponsor | National University Hospital, Singapore (other) |
| Locations | 1 site (Singapore) |
| Trial ID | NCT05984940 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the clinical outcomes of two different materials used in root canal treatments: Ortho MTA (BioMTA®) cement and the conventional gutta-percha combined with AH Plus® bioceramic sealer. The study will involve patients aged 21 to 95 who require root canal treatment for infected teeth, with a focus on evaluating healing outcomes. Participants will be randomly assigned to receive either treatment, and their progress will be monitored through follow-up assessments. The trial seeks to provide systematic evaluations of the effectiveness of Ortho MTA as a root filling material.
Who should consider this trial
Good fit: Ideal candidates are medically healthy adults aged 21 to 95 with infected teeth requiring root canal treatment.
Not a fit: Patients under 21 years old, pregnant women, or those with autoimmune diseases or uncontrolled diabetes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved healing outcomes for patients undergoing root canal treatments.
How similar studies have performed: While there have been comparisons of bioceramic materials in endodontics, the specific use of Ortho MTA cement in this context is novel and has not been systematically evaluated in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * A preoperative periapical radiograph will be required for diagnosis. * Subjects at least 21 years old to 95 years old. * Medically healthy * In a patient with multiple teeth requiring root canal treatment, only 1 tooth from each side will be included and selected at random. * Tooth requiring root canal treatment presenting with periapical radiolucency. Exclusion Criteria: * Patients below 21 years old. * Pregnant women. * Patients with autoimmune disease and uncontrolled diabetes. * Teeth with periodontal probing depth 5mm or more. * Incomplete root formation that is detected radiographically. * Cracked teeth. * Teeth are deemed to have poor restorative prognosis. * Teeth with adjacent teeth on the same side that require root canal treatment.
Where this trial is running
Singapore
- National University Hospital, Singapore — Singapore, Singapore (RECRUITING)
Study contacts
- Study coordinator: Siyi Choo
- Email: choosiyi@nus.edu.sg
- Phone: +65 82223285
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Endodontic Disease