Comparing oral hygiene methods for patients with full-arch dental implants

Analysis of the Effectiveness of the Use of Glycine Powder and Angled Implant Brush in Oral Hygiene Maintenance in Patients Reinstated With Columbus Bridge ProtocolTM: a Factorial Randomized Study

NA · A.O.U. Città della Salute e della Scienza · NCT05965076

This study is trying to find out which oral hygiene methods work best for people with full-arch dental implants to keep their mouths healthy.

Quick facts

PhaseNA
Study typeInterventional
Enrollment74 (estimated)
SexAll
SponsorA.O.U. Città della Salute e della Scienza (other)
Locations1 site (Torino)
Trial IDNCT05965076 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of different oral hygiene procedures in patients who have undergone the Columbus Bridge ProtocolTM for full-arch dental implants. A total of at least 74 participants will be randomly assigned to one of four groups, receiving either standard or glycine-based professional oral hygiene treatments, and using either a standard or angled toothbrush for home care. The study will measure bacterial plaque presence on dental implants and dentures before and after treatment, with follow-up assessments conducted after three months to analyze the differences in plaque levels. This approach aims to identify the most effective oral hygiene practices for maintaining dental health in these patients.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who are in good systemic health and have had Columbus Bridge ProtocolTM reinstatement for at least six months.

Not a fit: Patients with heavy smoking habits, autoimmune diseases, or other significant health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved oral hygiene practices that enhance dental health for patients with full-arch implants.

How similar studies have performed: Currently, there are no scientific studies that have explored this specific combination of oral hygiene methods in this patient population.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>= 18years
* Good systemic health, with ASA classification \<= 2
* Columbus Bridge ProtocolTM reinstation from at least six months

Exclusion Criteria:

* Heavy smokers (\>= 10 cigarettes per day)
* Pregnancy or breastfeeding
* Autoimmune diseases with or without oral involvement
* Biological complications on at least one of the dental implants
* Perimplantits diagnosis, defined according to Lindhe et al's criteria \[5\]
* Radicular bone \<4mm, evaluated by means of RX
* Use of gingival overgrowth inducing drugs
* Cognitive or motor impairments
* Full-arch reinstations performed in other structures
* Respiratory issues
* Infective diseases

Where this trial is running

Torino

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Plaque, Dental, glycine, airflow, full-arch, angled toothbrush

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.