Comparing oral Gemifloxacin and intravenous Cefotaxime for treating spontaneous bacterial peritonitis

Comparative Study Between the Efficacy of Oral Gemifloxacin and Intravenous Cefotaxime in Treatment of Spontaneous Bacterial Peritonitis

PHASE3 · Tanta University · NCT04168099

This study is testing whether taking Gemifloxacin by mouth works as well as getting Cefotaxime through an IV for treating people with spontaneous bacterial peritonitis.

Quick facts

PhasePHASE3
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorTanta University (other)
Locations1 site (Tanta)
Trial IDNCT04168099 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of oral Gemifloxacin with intravenous Cefotaxime in treating patients diagnosed with spontaneous bacterial peritonitis. It aims to determine which treatment option provides better outcomes for patients suffering from this condition. The study is interventional and is conducted in a Phase 3 setting, indicating a focus on confirming efficacy and monitoring side effects in a larger patient population.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with spontaneous bacterial peritonitis.

Not a fit: Patients with secondary peritonitis will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective or convenient treatment option for patients with spontaneous bacterial peritonitis.

How similar studies have performed: Other studies have explored antibiotic treatments for spontaneous bacterial peritonitis, but the specific comparison of oral Gemifloxacin and intravenous Cefotaxime is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with spontaneous bacterial peritonitis

Exclusion Criteria:

* secondary peritonitis

Where this trial is running

Tanta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Spontaneous Bacterial Peritonitis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.