Comparing open and laparoscopic surgery for perforated peptic ulcers

Open Versus Laparoscopic Repair of Perforated Peptic Ulcer in Sohag

NA · Sohag University · NCT06484699

This study is testing whether open surgery or laparoscopic surgery works better and is safer for people with perforated peptic ulcers.

Quick facts

PhaseNA
Study typeInterventional
Enrollment50 (estimated)
SexAll
SponsorSohag University (other)
Locations1 site (Sohag)
Trial IDNCT06484699 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the outcomes of two surgical techniques, open repair and laparoscopic repair, for patients with perforated peptic ulcers. The study will enroll patients diagnosed with this condition and assess the effectiveness and safety of each approach. By analyzing the results, the trial seeks to provide evidence-based guidance on the most appropriate surgical technique for treating perforated peptic ulcers at Sohag University Hospital.

Who should consider this trial

Good fit: Ideal candidates for this study are patients of any age with a clinical diagnosis of perforated peptic ulcer who are fit for surgery.

Not a fit: Patients with associated bleeding ulcers or other significant pathologies, as well as those with higher ASA grades, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help determine the best surgical approach for patients with perforated peptic ulcers, potentially leading to improved recovery and outcomes.

How similar studies have performed: Previous studies comparing surgical techniques for perforated peptic ulcers have shown varying results, indicating that this area of research is both relevant and necessary.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients with a clinical diagnosis of perforated peptic ulcer that are fit to undergo surgery either via laparotomy or laparoscopy, males or females, any age, with gastric or duodenal ulcer, with American Society of Anesthesiologists (ASA) grade I, II, III.

Exclusion Criteria:

* Patients with associated bleeding ulcer (additional steps are needed to control bleeding).
* Patients with associated pathology other than perforated peptic ulcer.
* Patients with American Society of Anesthesiologists (ASA) grade IV, V, VI.

Where this trial is running

Sohag

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Perforated Peptic Ulcer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.