Comparing ondansetron lozenge versus IV ondansetron to prevent shivering during cesarean section

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study compares two routes of giving ondansetron—a dissolvable lozenge and an intravenous injection—in parturient women undergoing cesarean delivery with spinal anesthesia. Participants who meet inclusion criteria receive one of the two ondansetron interventions before or during the operation, and clinicians monitor for intraoperative and postoperative shivering and related outcomes. The protocol excludes patients with preoperative fever or shivering, significant comorbidities, or contraindications to ondansetron. Outcomes likely include incidence and severity of shivering and common side effects such as nausea and vomiting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 18 to 40 years.
* American Society of Anesthesiology (ASA) physical status II.
* Parturient women undergoing cesarean section under spinal anesthesia.

Exclusion Criteria:

* Parturient women with any contraindication or hypersensitivity to the study drugs.
* Any history of cardiovascular diseases, psychosis, hypertension, fetal distress, cord prolapse initial.
* Preoperative shivering.
* Preoperative fever (\>38°C).
* Body mass index \> 40 kg/m2.
* Medical history of alcohol or drug abuse.
* Hypo- or hyperthyroidism.
* Parkinson's disease or any extrapyramidal disease.
* Intraoperative blood transfusion.

Where it's running

• Tanta University
  Tanta, El-Gharbia, Egypt Recruiting

Study contacts

• Study coordinator: Mohammed S Elsharkawy, MD
• Email: mselsharkawy@med.tanta.edu.eg
• Phone: 00201148207870

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Enhanced Recovery Adherence and Recovery Quality After Cesarean Delivery

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.