Comparing nylon and polyurethane epidural catheters for orthopedic surgery

Nylon Versus Polyurethane Epidural Catheters In Patients Undergoing Major Orthopedic Surgery

NA · Damanhour Teaching Hospital · NCT05168943

This study is testing whether nylon or polyurethane epidural catheters work better and have fewer problems for patients having major orthopedic surgery with continuous pain relief.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages21 Years to 60 Years
SexAll
SponsorDamanhour Teaching Hospital (other gov)
Locations1 site (Damanhūr, El-Beheira)
Trial IDNCT05168943 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the safety and efficacy of nylon (polyamide) epidural catheters versus polyurethane epidural catheters in patients undergoing major orthopedic surgery with continuous epidural anesthesia. It is a prospective, randomized, double-blind study involving 60 patients who will be randomly assigned to receive either type of catheter. The study will assess complications associated with catheter use, such as blockage, dysfunction, and breakage, to determine which material provides better outcomes for patients.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 21 to 60 years with an ASA physical status of II or lower and a BMI under 35.

Not a fit: Patients who are over 60 years old, have a BMI of 35 or higher, or have contraindications to regional anesthesia will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved safety and effectiveness of epidural anesthesia in orthopedic surgeries.

How similar studies have performed: While this study addresses a common issue in anesthesia, similar studies have not been widely reported, making this approach relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status ≤ II
* Age from 21 to 60 years
* Body Mass Index (BMI) \< 35

Exclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status \> II
* Age \< 21 years or \> 60 years
* Body Mass Index (BMI) ≥ 35
* Contraindications to regional anesthesia (including coagulopathy and infection at the injection site)
* Uncooperative patients
* Patients with known allergy to local anesthetics or opioids

Where this trial is running

Damanhūr, El-Beheira

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Epidural, Anesthesia, Catheter Complications, Catheter Blockage, Catheter Dysfunction, Catheter Breakage, Epidural Anesthesia, Nylon Epidural Catheter

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.