Comparing non-invasive FFR‑CT with invasive FFR in a multi-ethnic hospital population

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective analysis of CT coronary angiography (CTCA) records from Sandwell and West Birmingham NHS Trust between January 2019 and December 2023, focusing on roughly 500 adults with stable chest pain who underwent CTCA, FFR‑CT, and invasive FFR. The clinical team will screen the database for eligible patients with high-quality CT images and extract paired FFR‑CT and invasive FFR results for comparison. Statistical correlation and diagnostic performance (sensitivity, specificity, predictive values) will be calculated overall and across ethnic groups to assess real-world accuracy. The goal is to clarify variability seen in prior observational work and inform whether FFR‑CT can reliably reduce invasive testing in routine practice.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* •≥18 years

  * Stable •patients with suspected CAD
  * Patients who underwent CTCA, FFR CT and had an invasive FFR.
  * CTCA images of high-quality for analysis, with clear visualisation of coronary arteries and minimal artifacts.

Exclusion Criteria:

* •\<18 years of age

  * Did not undergo FFR CT
  * Inadequate quality/degraded CTCA images

Where it's running

• Sandwell and West Birmingham NHS Trust
  Birmingham, West Midlands, United Kingdom Recruiting

Study contacts

• Study coordinator: Vinoda Sharma, FRCP FESC FRCPE
• Email: vinodasharma@nhs.net
• Phone: 0044 1215075841

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.