Clinical trial Recruiting at 1 site Interventional Ages 21 to 65 Women only

Comparing nerve blocks for pain management in breast surgery

Official title: Comparison Between Ultrasound-guided Pectoral Nerve Blocks, Thoracic Erector Spinae Plane Block and Serratus Anterior Plane Block for Breast Surgery: A Prospective Randomized Study

Run by Tanta University · NCT06947642 · Data updated 2026-11-12

This study is testing which of three different nerve blocks can help women aged 21 to 65 manage pain better after breast surgery.

Quick facts

Study typeInterventional
Ages21 Years to 65 Years
SexWomen only
Enrollment60 (estimated)
SponsorTanta University
Academic / other
Locations1 site (Tanta, El-Gharbia)
StatusRecruiting
StartedApril 30, 2025
Main results expectedSeptember 30, 2026
Study endsSeptember 30, 2026
Registry record updatedMay 20, 2025
Trial IDNCT06947642 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are females aged 21 to 65 years old, classified as ASA physical status I or II, who are scheduled for elective breast surgeries under general anesthesia.

Probably not a fit

Patients who may not benefit from this study include those with a BMI of 35 kg/m2 or higher, those with coagulation abnormalities, or those with psychiatric disorders that affect communication.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness of three ultrasound-guided regional anesthetic techniques—Pectoral nerve block, Erector Spinae Plane block, and Serratus Anterior Plane block—in managing postoperative pain for patients undergoing elective breast surgeries. The research focuses on improving pain control, as inadequate management can lead to chronic pain and reliance on opioids, which have undesirable side effects. By utilizing these fascial plane blocks, the study seeks to reduce surgical stress response and enhance recovery outcomes for patients. The study will involve female participants aged 21 to 65 who are classified as ASA physical status I or II.

Why it matters

Potential benefit: If successful, this study could significantly improve postoperative pain management for breast surgery patients, reducing reliance on opioids and enhancing recovery.

How similar studies have gone: Previous studies have shown the efficacy of similar fascial plane blocks in managing postoperative pain, indicating that this approach is supported by existing evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

• Age from 21 to 65 years old female, American Society of Anesthesiologists (ASA) physical status I or II, who will undergo breast surgeries under general anesthesia.

Exclusion Criteria:

* Patient refusal to participate in research.
* Body Mass Index (BMI) ≥35 kg/m2.
* Sensitivity to the intervention drugs.
* Coagulation abnormalities.
* Psychiatric disorder and communication difficulties.
* Chronic neurological disease.
* Any skin infection at the needle puncture site.
* Chest wall deformity

Where it's running

  • Tanta University
    Tanta, El-Gharbia, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.