Comparing needling and microneedling treatments for vitiligo

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of two treatment methods—needling and microneedling—followed by narrowband UVB therapy in patients with localized stable non-segmental vitiligo. A total of 80 participants aged 15 to 60 will be randomly assigned to receive either needling or microneedling, with the primary outcome being the percentage of skin repigmentation assessed at 12 weeks. Secondary outcomes will monitor potential adverse effects such as erythema and scarring. The study seeks to provide insights into which method may offer better results for vitiligo patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Both male and female
* Age 15-60 years
* Patients having vitiligo for more than 1 year

Exclusion Criteria:

* Patients with tendency of keloid formation or hypertrophic scarring
* Patients with any bleeding disorder, coagulation defect or using anti platelets
* Any local infection at the treatment site
* Patients who had received systemic therapy in last 6 months

Where it's running

• Khyber Teaching Hospital
  Peshawar, Khyber Pakhtunkhwa, Pakistan Recruiting

Study contacts

• Principal investigator: Huma Gul Doctor, MBBS — Khyber Teaching Hospital
• Study coordinator: Huma Gul Doctor, MBBS
• Email: xaffar965@gmail.com
• Phone: +923471927046

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• crisaborole 2% versus tacrolimus 0.1% with light therapy for facial vitiligo

  This study tests whether applying crisaborole 2% ointment can improve stable facial vitiligo in children and adults and whether it is as safe and effective as tacrolimus 0.1% when combined with light therapy.

  Recruiting Phase 3 Cairo University · Cairo · NCT07904910

• Imaging vitiligo lesions with polarized, sub-ultraviolet, and ultraviolet dermoscopy

  This study tests whether advanced light-based skin imaging can reveal details of vitiligo spots in adults more clearly than standard polarized dermoscopy.

  Recruiting Istanbul Training and Research Hospital · Istanbul · NCT07846969

• MH004 Ointment in non-segmental vitiligo: a phase 3 trial

  A 12-month randomized trial tests MH004 ointment to see if it helps facial vitiligo more than a placebo in people aged 12 to 75.

  Recruiting Phase 3 Minghui Pharmaceutical (Hangzhou) Ltd · Beijing, Beijing Municipality · NCT07682506

• Test of ACT-777991 in adults with non-segmental vitiligo

  This study tests whether ACT-777991 can help restore skin color in adults with non-segmental vitiligo, compared to placebo.

  Recruiting Phase 2 Idorsia Pharmaceuticals Ltd. · Los Angeles, California and 4 other locations · NCT07667569

• NSV: Vitiligo Drug Safety and Effectiveness Registry for Adults and Teens

  This registry tracks adults and teens with nonsegmental vitiligo to see how usual treatments work and how safe they are over time in real-world dermatology care.

  Recruiting CorEvitas · Waltham, Massachusetts · NCT07659418

• D-2570 in Non-Segmental Vitiligo (Phase 2)

  This study tests whether D-2570 can improve skin discoloration in adults with non-segmental vitiligo compared with a placebo.

  Recruiting Phase 2 InventisBio Co., Ltd · Shanghai, Shanghai Municipality · NCT07625891

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.