Comparing needling and microneedling treatments for vitiligo
Puncture to Repigment: A Comparative Analysis Of Needling vs. Microneedling Along With NBUVB in Treatment of Non-Segmental Vitiligo
This study is testing whether needling or microneedling treatments, followed by light therapy, can help people with stable vitiligo see better skin color improvement.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 15 Years to 60 Years |
| Sex | All |
| Sponsor | Khyber Teaching Hospital Academic / other |
| Locations | 1 site (Peshawar, Khyber Pakhtunkhwa) |
| Trial ID | NCT06991972 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of two treatment methods—needling and microneedling—followed by narrowband UVB therapy in patients with localized stable non-segmental vitiligo. A total of 80 participants aged 15 to 60 will be randomly assigned to receive either needling or microneedling, with the primary outcome being the percentage of skin repigmentation assessed at 12 weeks. Secondary outcomes will monitor potential adverse effects such as erythema and scarring. The study seeks to provide insights into which method may offer better results for vitiligo patients.
Who should consider this trial
Good fit: Ideal candidates are males and females aged 15-60 years with localized stable vitiligo lasting more than one year.
Not a fit: Patients with a tendency for keloid formation, bleeding disorders, or recent systemic therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective treatment options for patients with localized vitiligo, improving their skin appearance and quality of life.
How similar studies have performed: While there have been studies on microneedling and phototherapy, this specific comparison of needling versus microneedling in vitiligo is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Both male and female * Age 15-60 years * Patients having vitiligo for more than 1 year Exclusion Criteria: * Patients with tendency of keloid formation or hypertrophic scarring * Patients with any bleeding disorder, coagulation defect or using anti platelets * Any local infection at the treatment site * Patients who had received systemic therapy in last 6 months
Where this trial is running
Peshawar, Khyber Pakhtunkhwa
- Khyber Teaching Hospital — Peshawar, Khyber Pakhtunkhwa, Pakistan (Recruiting)
Study contacts
- Principal investigator: Huma Gul Doctor, MBBS — Khyber Teaching Hospital
- Study coordinator: Huma Gul Doctor, MBBS
- Email: xaffar965@gmail.com
- Phone: +923471927046
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.