Comparing nasal and oral breathing during drug-induced and natural sleep

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the relationship between the route of breathing (nasal vs oral) and airway collapsibility in patients with obstructive sleep apnea (OSA). Participants will undergo a drug-induced sleep endoscopy (DISE) to determine their breathing route as a percentage of total breaths during different sleep states. Additionally, an in-laboratory polysomnogram will be performed to assess breathing patterns using a specialized cannula. The findings will help clarify whether breathing routes during DISE accurately reflect those during natural sleep.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • Adults (≥ 18yrs) that underwent clinical evaluation at the CPAP Alternatives Clinic at Penn Otorhinolaryngology.

  * Must have at least mild OSA (AHI\>5)

Exclusion Criteria:

* • Sleep study with an AHI\<5, \>25% of total events being central or mixed events, or inability to achieve adequate drug-induced sleep.

  * Upper Respiratory Illness at the time of the DISE.

Where it's running

• Hospital at the University of Pennsylvania
  Philadelphia, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Julianna Rodin, MD — University of Pennsylvania
• Study coordinator: Everett Seay
• Email: seaye@pennmedicine.upenn.edu
• Phone: 215-662-2777

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.