Comparing nasal airflow measurements after endoscopic nasal surgery

Assessment of Nasal Obstruction, a Comparison Between Rhinomanometry and Nasal Inspiratory Peak Flow at Patients After Endoscopic Nasal Surgery

NA · University Hospital Ostrava · NCT05921396

This study is testing if a new way to measure how well air flows through the nose can show changes in breathing before and after nasal surgery for patients with pituitary adenomas.

Quick facts

PhaseNA
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorUniversity Hospital Ostrava (other)
Locations1 site (Ostrava, Moravian-Silesian Region)
Trial IDNCT05921396 on ClinicalTrials.gov

What this trial studies

This project aims to evaluate whether nasal inspiratory peak flow can effectively measure nasal patency before and after endoscopic nasal surgery, compared to the traditional method of rhinomanometry. The study focuses on patients with pituitary adenomas who require surgical intervention through the nasal cavity. By assessing airflow changes, the research seeks to understand the impact of surgical procedures on nasal functions and overall patient quality of life. The study will involve adult participants who meet specific inclusion criteria and will be conducted at the University Hospital Ostrava.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old with a diagnosis of pituitary adenoma who are indicated for endoscopic transnasal surgery.

Not a fit: Patients who have previously undergone nasal cavity or skull base surgery, have nasal diseases, olfactory disorders, or require septoplasty may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a less invasive and more accessible method for assessing nasal airflow, improving postoperative care for patients undergoing nasal surgery.

How similar studies have performed: Other studies have shown success in using nasal airflow measurements for assessing nasal function, but this specific comparison of methods is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age over 18 years
* patients with pituitary adenoma indicated to endoscopic transnasal extirpation of the pituitary adenoma

Exclusion Criteria:

* patients after surgery of the nasal cavity or base of the skull
* patients with nasal disease and paranasal sinuses
* patients with olfactory disorders before surgery
* patients with nasal septal deviation that requires septoplasty

Where this trial is running

Ostrava, Moravian-Silesian Region

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Pituitary Adenoma Invasive, Nasal Obstruction, Pituitary Adenoma, Nasal surgery, Rhinomanometry, Nasal inspiratory peak flow, Endoscopic nasal surgery

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.