Comparing muscle recovery measurements at the hand and foot
Comparison of the TOFscan Simultaneous Measures at the Thumb and the First Toe During Recovery of Neuromuscular Function Following Rocuronium Administration
This study is testing whether using sensors on the foot can give the same reliable information about muscle recovery as using sensors on the hand after anesthesia, to help improve patient care during recovery from surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ciusss de L'Est de l'Île de Montréal Academic / other |
| Locations | 1 site (Montréal, Quebec) |
| Trial ID | NCT06236763 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of using accelerometers placed on both the hand and foot to measure neuromuscular recovery after administration of rocuronium during general anesthesia. The researchers believe that measurements taken from the foot can provide reliable data similar to those taken from the hand, especially in situations where hand monitoring is compromised. By comparing the readings from both locations, the study seeks to establish a more accurate method for assessing neuromuscular blockade recovery in patients undergoing elective surgery. The findings could enhance monitoring techniques in anesthesiology, ensuring better patient outcomes during recovery.
Who should consider this trial
Good fit: Ideal candidates include ASA 1-3 patients over 18 years old undergoing elective surgery with general anesthesia and rocuronium.
Not a fit: Patients with renal or hepatic dysfunction, neuromuscular diseases, or those requiring CPAP for obstructive sleep apnea may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring of neuromuscular recovery, enhancing patient safety during anesthesia.
How similar studies have performed: While the approach of using accelerometers for neuromuscular monitoring is established, this specific comparison of hand and foot measurements is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA 1-3 patients * Elective surgery * Undergoing general anesthesia with rocuronium induced NMB * BMI \< 36 kg.m-2 * Age \> 18 years old * French or English speaking patient Exclusion Criteria: * Renal or hepatic dysfunction * Obstructive sleep apnea requiring continuous positive airway pressure (CPAP) machine * Neuromuscular disease * Peripheral arterial disease (suspected, known or investigated) * Calcium channel anomalies * Hypothermia (\< 35C) * Hyper/hypomagnasemia * Allergy to any drug used in the study protocol * Patient refusal
Where this trial is running
Montréal, Quebec
- Maisonneuve-Rosemont Hospital - CIUSSS de l'Est de l'Ile de Montréal — Montréal, Quebec, Canada (Recruiting)
Study contacts
- Principal investigator: 514-252-3426 Fortier, MD — Maisonneuve-Rosemont Hospital - CIUSSS de l'Est de l'Ile de Montréal
- Study coordinator: Louis-Philippe Fortier, MD
- Email: lpfortier.hmr@ssss.gouv.qc.ca
- Phone: 514-252-3426
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.