Comparing MTA versus Biodentine for complete pulpotomy in painful molars

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 18–40 who present with moderate to severe pain from cariously exposed maxillary or mandibular molars and meet diagnostic tests for symptomatic irreversible pulpitis will be treated at Dow University of Health Sciences. Treatment is done by one dentist over two visits with local anesthesia and rubber-dam isolation; the coronal pulp is removed, bleeding controlled within 10 minutes, and then either MTA or Biodentine is placed. Pain will be recorded on a 1–10 scale and baseline tests include cold test, electric pulp testing, and a periapical radiograph; follow-up focuses on short-term clinical outcomes. The trial compares the two biomaterials' performance for complete pulpotomy in this specific patient group at a single center in Karachi.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Teeth of generally healthy patients having following criteria will be included:

1. Age between 18-40 years of both males and females
2. Carious exposed maxillary and mandibular molars teeth
3. Moderate to severe pain (VAS 4-10)
4. Diagnosed with Symptomatic irreversible pulpitis on cold test and Electric pulp test (EPT)
5. Periapical index of 1
6. Hemostasis is achieved within 10 mins after full pulpotomy

Exclusion Criteria:

Teeth of generally healthy patients having following criteria will be excluded:

1. Any traumatic injury
2. Non-restorable carious lesion
3. Immature or Open apices of roots
4. Internal or external Resorption
5. Calcified canals

Where it's running

• Dr Khadija Zubair
  Karachi, Sindh, Pakistan Recruiting
• Dr Khadija Zubair
  Karachi, Sindh, Pakistan Recruiting

Study contacts

• Principal investigator: Dr Khadija Zubair, Postgraduate Trainee- FCPS — Dow University of Health Sciences
• Study coordinator: Dr Khadija Zubair, Postgraduate trainee- FCPS
• Email: khadija.zubair21@yahoo.com
• Phone: 03363605145

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.