Comparing MTA and Biodentine for treating children's teeth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective interventional study aims to evaluate the clinical and radiographic success of two medicaments, mineral trioxide aggregate (MTA) and Biodentine, in vital pulp therapy for primary molars in children aged 2 to 12. The study employs a randomized split-mouth design, where each child will receive one treatment on one side of their mouth and the other treatment on the opposite side. Participants will be monitored for clinical and radiographic outcomes every six months for three years following the procedures. The research is conducted in accordance with the standards set by the American Academy of Pediatric Dentistry at Geisinger Medical Center and Geisinger Bloomsburg Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female patients ages of 2 to ≤12 years.
* Bilateral symptomatic or asymptomatic vital primary molars with caries approximating or into the pulp.
* Patient who need a pulpotomy and/or indirect pulp cap treatments in two or more quadrants.
* Parents of patients who can provide consent in English.
* Patients who need treatment in an operating room setting at Geisinger.

Exclusion Criteria:

* Pre-operative radiographic or clinical symptoms associated with irreversible pulpitis or necrotic pulp.
* Radiographs not displaying furcation region of the tooth.
* Patients with cardiac conditions who need prophylaxis for infective Endocarditis.
* Patients with any type of cancer in the past or present.
* Non-restorable molars.

Where it's running

• Geisinger
  Danville, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Gayatri Malik, DMD — Geisinger Clinic
• Study coordinator: Gayatri Malik, DMD
• Email: gmalik1@geisinger.edu
• Phone: 570-271-6355

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing stainless steel and zirconia crowns for children's teeth

  This study is testing whether stainless steel crowns or zirconia crowns work better and make parents happier for kids aged 4 to 5 who need dental crowns on their back teeth.

  Recruiting Aydin Adnan Menderes University · Aydin, Aydın · NCT06685640

• Evaluating a new pulp treatment for children's primary molars

  This study is testing a new dental treatment for kids aged 4 to 9 to see if a special material called Neo-Putty® works better than the usual method for saving their baby teeth.

  Recruiting October University for Modern Sciences and Arts · El-Sheikh Zayed City, Giza Governorate · NCT06288477

• Peer recovery support to help people stay on medication for opioid use disorder

  This project will see if meeting with trained peer recovery supporters helps people with opioid use disorder stay on their medication treatment.

  Recruiting Geisinger Clinic · Danville, Pennsylvania · NCT07197801

• Informing low-acuity ED patients about non-emergency care options

  This project will test whether sending a text message and adding information to your after-visit summary helps adults discharged from the ED with low-acuity visits use primary care or an intelligent triage tool instead of returning to the emergency department.

  Recruiting Geisinger Clinic · Danville, Pennsylvania · NCT07185828

• Angiography versus electrogram guidance for Bachmann bundle pacemaker lead placement

  This study will try two ways to guide placement of an atrial pacemaker wire in the Bachmann bundle for people getting a permanent pacemaker or ICD to see which method leads to more successful placement.

  Recruiting Geisinger Clinic · Wilkes-Barre, Pennsylvania · NCT07110922

• Nurse follow-up nudge to reduce emergency visits after ambulatory-sensitive diagnoses

  This project will test whether a nurse follow-up message or phone call after a clinic visit can reduce emergency department visits among adults (30+) diagnosed with ambulatory sensitive conditions.

  Recruiting Geisinger Clinic · Danville, Pennsylvania · NCT07028398

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.