Comparing MRI sensitivity for acute brain microinfarctions
Sensitivity Comparison of Follow-up MRI Between Acute Cerebral and Cerebellar Cortical Microinfarctions ( CMI )
Centre Hospitalier Universitaire de Nīmes · NCT06218576
This study is testing how well follow-up MRIs can find tiny brain injuries in patients who have already had symptoms of a stroke.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 59 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Nīmes (other) |
| Locations | 1 site (Nîmes) |
| Trial ID | NCT06218576 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the sensitivity of follow-up MRI in detecting acute cerebral and cerebellar cortical microinfarctions (CMI) in patients. It focuses on patients who have experienced symptomatic brain infarctions and had initial MRIs performed shortly after symptom onset. The study will analyze the persistence of MRI signal changes over time, particularly in patients with small-sized CMIs. By examining the temporal dynamics of MRI signals, the study seeks to provide insights into the detection rates of these microinfarctions.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who have experienced a symptomatic brain infarction and had an MRI within one week of symptom onset.
Not a fit: Patients under 18 years old will not benefit from this study as they do not meet the eligibility criteria.
Why it matters
Potential benefit: If successful, this study could improve the diagnostic accuracy and follow-up care for patients with acute cerebral and cerebellar microinfarctions.
How similar studies have performed: While there have been limited studies on the sensitivity of MRI for acute CMIs, this study's specific focus on acute cases and its observational nature may provide novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients admitted to our stroke centre between February 2021 and June 2023 with the following inclusion criteria: * age \>18 years, * initial MRI performed within one week after symptom onset, * symptomatic brain infarction confirmed by DWI, * presence of acute cerebral and/or cerebellar CMI Exclusion Criteria: * age \< 18 years
Where this trial is running
Nîmes
- CHU de Nîmes — Nîmes, France (RECRUITING)
Study contacts
- Study coordinator: Dimitri RENARD
- Email: dimitri.renard@chu-nimes.fr
- Phone: +33466685808
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Acute Cerebral and Cerebellar Cortical Microinfarctions